HEPTAETHYLENE GLYCOL MONOMETHYL ETHER

Base Information

• Chemical Name: HEPTAETHYLENE GLYCOL MONOMETHYL ETHER
• CAS No.: 4437-01-8
• Molecular Formula: C15H32O8
• Molecular Weight: 340.414
• Hs Code.: 29094990
• Mol file: 4437-01-8.mol

Synonyms:2,5,8,11,14,17,20-Heptaoxadocosan-22-ol(6CI,8CI,9CI);Emkanol M 350;Ethanol,2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-;Heptaethylene glycol, monomethyl ether;Methoxyheptaethylene glycol;

Chemical Property of HEPTAETHYLENE GLYCOL MONOMETHYL ETHER

Chemical Property:

• Vapor Pressure: 1.16E-08mmHg at 25°C
• Refractive Index: 1.448
• Boiling Point: 416 °C at 760 mmHg
• PKA: 14.36±0.10(Predicted)
• Flash Point: 205.4 °C
• PSA: 84.84000
• Density: 1.069 g/cm³
• LogP: -0.27530
• Storage Temp.: -20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Heptaethylene Glycol Monomethyl Ether >97.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: m-PEG7-alcohol is a PEG linker containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.
• Uses: Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization

Technology Process of HEPTAETHYLENE GLYCOL MONOMETHYL ETHER

There total 2 articles about HEPTAETHYLENE GLYCOL MONOMETHYL ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3,6,9,12,15,18,21-heptaoxadocosan-1-ol (4437-01-8) + 4-Nitrobenzenesulfonyl chloride (98-74-8)

Guidance literature:

Reference yield:

Tetraethylene glycol (112-60-7) + 1-chloro-3,6,9-trioxadecane (52995-76-3) → 3,6,9,12,15,18,21-heptaoxadocosan-1-ol (4437-01-8)

Guidance literature:

With sodium; Yield given. Multistep reaction; 1) 100-120 deg C, 2) 100-120 deg C, 2-3 h;

Reference yield: 100.0%

3,6,9,12,15,18,21-heptaoxadocosan-1-ol (4437-01-8) + p-toluenesulfonyl chloride (98-59-9) → 2,5,8,11,14,17,20-heptaoxadocosan-22-yl 4-methylbenzene-1-sulfonate (79622-11-0)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; for 8h; Cooling with ice;

DOI:10.1002/asia.200900679

upstream raw materials:

Tetraethylene glycol

1-chloro-3,6,9-trioxadecane

Downstream raw materials:

2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-ol

2,5,8,11,14,17,20-heptaoxadocosan-22-yl 4-methylbenzene-1-sulfonate

22-bromo-2,5,8,11,14,17,20-heptaoxadocosane

20-methoxy-1-(methylsulfonyl)oxy-3,6,9,12,15,18-hexaoxaeicosane

Refernces

• 1、 -. "Tetraiodopyrrole derivatives as contrast medium and as antiseptic". . . Retrieved 2008/06/13.