1H,5H-Benzo(ij)quinolizinium, 2,3,6,7-tetrahydro-9-(hydroxymethyl)-4-m ethyl-, iodide

Base Information

• Chemical Name: 1H,5H-Benzo(ij)quinolizinium, 2,3,6,7-tetrahydro-9-(hydroxymethyl)-4-m ethyl-, iodide
• CAS No.: 101077-29-6
• Molecular Formula: C₁₄H₂₀NO*I
• Molecular Weight: 345.223
• Mol file: 101077-29-6.mol

Synonyms:1H,5H-Benzo[ij]quinolizinium,2,3,6,7-tetrahydro-9-(hydroxymethyl)-4-methyl-, iodide (9CI)

Chemical Property of 1H,5H-Benzo(ij)quinolizinium, 2,3,6,7-tetrahydro-9-(hydroxymethyl)-4-m ethyl-, iodide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 20.23000
• Density: g/cm³
• LogP: -0.88780

Purity/Quality:

98%min ^*data from raw suppliers

1H,5H-BENZO(IJ)QUINOLIZINIUM, 2,3,6,7-TETRAHYDRO-9-(HYDROXYMETHYL)-4-M ETHYL-, IODIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H,5H-Benzo(ij)quinolizinium, 2,3,6,7-tetrahydro-9-(hydroxymethyl)-4-m ethyl-, iodide

There total 3 articles about 1H,5H-Benzo(ij)quinolizinium, 2,3,6,7-tetrahydro-9-(hydroxymethyl)-4-m ethyl-, iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

julolidine (479-59-4) → 9-hydroxymethyl-4-methyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolinium; iodide (101077-29-6)

Guidance literature:

Multi-step reaction with 3 steps

1: diethyl ether; phosphoryl chloride

2: diethyl ether; lithium alanate

3: acetone

With lithium aluminium tetrahydride; diethyl ether; acetone; trichlorophosphate;

DOI:10.1021/jo50009a015

Reference yield:

9-julolidinecarboxaldehyde (33985-71-6) → 9-hydroxymethyl-4-methyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolinium; iodide (101077-29-6)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether; lithium alanate

2: acetone

With lithium aluminium tetrahydride; diethyl ether; acetone;

DOI:10.1021/jo50009a015

Reference yield:

(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)-methanol (101077-18-3) + methyl iodide (74-88-4) → 9-hydroxymethyl-4-methyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolinium; iodide (101077-29-6)

Guidance literature:

With acetone;

DOI:10.1021/jo50009a015

upstream raw materials:

(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)-methanol

methyl iodide

julolidine

9-julolidinecarboxaldehyde