N-tert-Butyloxycarbonyl-dl-azidoalanine, tert-butyl ester

Base Information

Chemical Name:N-tert-Butyloxycarbonyl-dl-azidoalanine, tert-butyl ester
CAS No.:108283-48-3
Molecular Formula:C₁₂H₂₂N₄O₄
Molecular Weight:286.331
Hs Code.:
DSSTox Substance ID:DTXSID10148482
Wikidata:Q83014023

Synonyms:CCRIS 1796;N-tert-Butyloxycarbonyl-dl-azidoalanine, tert-butyl ester;108283-48-3;DTXSID10148482;LS-188960

Suppliers and Price of N-tert-Butyloxycarbonyl-dl-azidoalanine, tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of N-tert-Butyloxycarbonyl-dl-azidoalanine, tert-butyl ester

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:286.16410520
Heavy Atom Count:20
Complexity:416

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)OC(C)(C)C)N(C(=O)OC(C)(C)C)N=[N+]=[N-]
Isomeric SMILES:C[C@@H](C(=O)OC(C)(C)C)N(C(=O)OC(C)(C)C)N=[N+]=[N-]

Technology Process of N-tert-Butyloxycarbonyl-dl-azidoalanine, tert-butyl ester

There total 14 articles about N-tert-Butyloxycarbonyl-dl-azidoalanine, tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 459871-14-8
tert-butyl(2S)-[(tert-butoxycarbonyl)amino]-3-phenylmethanesulfonyloxypropionate

: 108492-14-4,108283-48-3
tert-butyl (S)-3-azido-2-((tert-butoxycarbonyl)amino)propanoate

Guidance literature:: With sodium azide; tetrabutylammomium bromide; In N,N-dimethyl-formamide; at 70 ℃; for 0.166667h;
DOI:10.1021/ja012741l

Reference yield: 50.0%

: 124-63-0
methanesulfonyl chloride

: 71630-31-4
(R)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate

: 108283-48-3
tert-butyl 2-(R)-(tert-butoxycarbonylamino)-3-azidopropanoate

: 107082-54-2
N-(tert-butyloxycarbonyl)-α,β-dehydroalanine tert-butyl ester

Guidance literature:: methanesulfonyl chloride; (R)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate; With triethylamine; In dichloromethane; at 0 ℃; for 0.5h;

With sodium azide; In dimethylsulfoxide-d6; at 70 ℃; Reagent/catalyst;
DOI:10.1002/psc.2968

Reference yield: 47.0%

: 71630-31-4,7738-22-9
N-(tert-butyloxycarbonyl)-L-serine tert-butyl ester

: 124-63-0
methanesulfonyl chloride

: 107082-54-2
N-(tert-butyloxycarbonyl)-α,β-dehydroalanine tert-butyl ester

: 108492-14-4,108283-48-3
tert-butyl (S)-3-azido-2-((tert-butoxycarbonyl)amino)propanoate

Guidance literature:: N-(tert-butyloxycarbonyl)-L-serine tert-butyl ester; methanesulfonyl chloride; With triethylamine; In dichloromethane; at 0 ℃; for 0.5h;

With sodium azide; In dimethylsulfoxide-d6; at 70 ℃; Reagent/catalyst;
DOI:10.1002/psc.2968