Benzenepentanoic acid, 4-bromo-, methyl ester

Base Information

Chemical Name:Benzenepentanoic acid, 4-bromo-, methyl ester
CAS No.:490035-81-9
Molecular Formula:C12H15BrO2
Molecular Weight:271.154
Hs Code.:

Synonyms:

Suppliers and Price of Benzenepentanoic acid, 4-bromo-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of Benzenepentanoic acid, 4-bromo-, methyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzenepentanoic acid, 4-bromo-, methyl ester

There total 11 articles about Benzenepentanoic acid, 4-bromo-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 67-56-1
methanol

: 22647-95-6
5-(4-bromophenyl)pentanoic acid

: 490035-81-9
methyl 5-(4-bromophenyl)pentanoate

Guidance literature:: 5-(4-bromophenyl)pentanoic acid; With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 1h; Inert atmosphere;

methanol; With potassium carbonate; In dichloromethane; at 20 ℃; for 2h;

Reference yield: 54.0%

: 5467-74-3
4-Bromophenylboronic acid

: C₁₅H₁₁Cl₄NO₆

: 490035-81-9
methyl 5-(4-bromophenyl)pentanoate

Guidance literature:: With nickel(II) chloride hexahydrate; triethylamine; 4,4'-di-tert-butyl-2,2'-bipyridine; In 1,4-dioxane; N,N-dimethyl-formamide; at 85 ℃; for 12h; Inert atmosphere;
DOI:10.1002/anie.201605463

Reference yield:

: 1122-91-4
4-bromo-benzaldehyde

: 490035-81-9
methyl 5-(4-bromophenyl)pentanoate

Guidance literature:: Multi-step reaction with 5 steps

1.1: 67 percent / diethyl ether / 2.25 h / -70 - 20 °C

2.1: 73 percent / sodium hydrogensulfate; p-hydroquinone; 4-tert-butylcatechol / diethyl ether / 3 h / 200 °C

3.1: BMS / bis-(2-methoxy-ethyl) ether / 0 - 140 °C

3.2: aq. NaOH; H₂O₂ / 25 - 50 °C

4.1: CrO₃; aq. H₂SO₄ / acetone / 20 °C

5.1: 73 percent / thionyl chloride / Heating

With chromium(VI) oxide; sodium hydrogen sulfate; thionyl chloride; dimethylsulfide borane complex; sulfuric acid; 4-tert-Butylcatechol; hydroquinone; In diethyl ether; diethylene glycol dimethyl ether; acetone;
DOI:10.1016/S0022-328X(02)01383-9