Isoquinoline, 1-(4-methylphenyl)-, 2-oxide

Base Information

Chemical Name:Isoquinoline, 1-(4-methylphenyl)-, 2-oxide
CAS No.:494749-16-5
Molecular Formula:C16H13NO
Molecular Weight:235.285
Hs Code.:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Isoquinoline, 1-(4-methylphenyl)-, 2-oxide

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Technology Process of Isoquinoline, 1-(4-methylphenyl)-, 2-oxide

There total 11 articles about Isoquinoline, 1-(4-methylphenyl)-, 2-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1532-72-5
isoquinoline N-oxide

: 29540-83-8
p-tolyl triflate

: 494749-16-5
1-(p-tolyl)isoquinoline N-oxide

Guidance literature:: With rubidium carbonate; palladium diacetate; tricyclohexylphosphine tetrafluoroborate; Trimethylacetic acid; In toluene; at 100 ℃; for 15h; Inert atmosphere;
DOI:10.1016/j.tet.2009.03.077

Reference yield: 74.0%

: 101273-46-5
1-(4′-methylphenyl)isoquinoline

: 494749-16-5
1-(p-tolyl)isoquinoline N-oxide

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃;
DOI:10.1246/cl.180429

Reference yield: 70.0%

: 1532-72-5
isoquinoline N-oxide

: 539-44-6
N-4-methylphenylhydrazine

: 1127562-09-7
3-(p-tolyl)isoquinoline N-oxide

: 494749-16-5
1-(p-tolyl)isoquinoline N-oxide

Guidance literature:: With potassium permanganate; In acetonitrile; at 90 ℃; for 1h; regioselective reaction; Schlenk technique;
DOI:10.1016/j.tet.2016.11.070