1H-Pyrrole-1-ethanol, 2-methyl-5-[4-(methylthio)phenyl]-,methanesulfonate (ester)

Base Information

Chemical Name:1H-Pyrrole-1-ethanol, 2-methyl-5-[4-(methylthio)phenyl]-,methanesulfonate (ester)
CAS No.:494850-87-2
Molecular Formula:C15H19NO3S2
Molecular Weight:325.453
Hs Code.:
Mol file:494850-87-2.mol

Synonyms:Saroglitazar INT;methanesulfonic acid 2-[2-methyl-5-(4-methylsulfanyl-phenyl)-pyrrol-1-yl]-ethyl ester

Suppliers and Price of 1H-Pyrrole-1-ethanol, 2-methyl-5-[4-(methylthio)phenyl]-,methanesulfonate (ester)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1H-Pyrrole-1-ethanol, 2-methyl-5-[4-(methylthio)phenyl]-,methanesulfonate (ester)

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 1H-Pyrrole-1-ethanol, 2-methyl-5-[4-(methylthio)phenyl]-,methanesulfonate (ester)

There total 5 articles about 1H-Pyrrole-1-ethanol, 2-methyl-5-[4-(methylthio)phenyl]-,methanesulfonate (ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 189501-33-5
1-[4-(methylthio)phenyl]pentane-1,4-dione

: 494850-87-2
methanesulfonic acid 2-[2-methyl-5-(4-methylsulfanyl-phenyl)-pyrrol-1-yl]-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Trimethylacetic acid / toluene / 105 - 115 °C

2: triethylamine / toluene / 2 h / 10 - 45 °C

With triethylamine; Trimethylacetic acid; In toluene; 1: |Paal-Knorr Pyrrole Synthesis;

Reference yield:

: 494850-27-0
C₁₄H₁₇NOS

: 124-63-0
methanesulfonyl chloride

: 494850-87-2
methanesulfonic acid 2-[2-methyl-5-(4-methylsulfanyl-phenyl)-pyrrol-1-yl]-ethyl ester

Guidance literature:: With triethylamine; In toluene; at 10 - 45 ℃; for 2h;

Reference yield:

: 42445-46-5
2-bromo-1-(4-methylsulfanyl-phenyl)-ethanone

: 494850-87-2
methanesulfonic acid 2-[2-methyl-5-(4-methylsulfanyl-phenyl)-pyrrol-1-yl]-ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium methylate / toluene / 1 h / 8 - 12 °C / Inert atmosphere

1.2: 0.5 h / 30 - 35 °C

2.1: sodium hydroxide / water; methanol; toluene / 1 h / 50 - 55 °C

2.2: 45 - 55 °C

3.1: Trimethylacetic acid / toluene / 105 - 115 °C

4.1: triethylamine / toluene / 2 h / 10 - 45 °C

With sodium methylate; triethylamine; sodium hydroxide; Trimethylacetic acid; In methanol; water; toluene; 3.1: |Paal-Knorr Pyrrole Synthesis;