N-[(3-Phenyl-3-oxetanyl)methyl]benzamide

Base Information

Chemical Name:N-[(3-Phenyl-3-oxetanyl)methyl]benzamide
CAS No.:497239-46-0
Molecular Formula:C17H17NO2
Molecular Weight:267.327
Hs Code.:
DSSTox Substance ID:DTXSID101275936
Nikkaji Number:J1.805.800F

Synonyms:DTXSID101275936;497239-46-0;N-[(3-Phenyl-3-oxetanyl)methyl]benzamide

Suppliers and Price of N-[(3-Phenyl-3-oxetanyl)methyl]benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[(3-Phenyl-3-oxetanyl)methyl]benzamide

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:267.125928785
Heavy Atom Count:20
Complexity:326

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(CO1)(CNC(=O)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of N-[(3-Phenyl-3-oxetanyl)methyl]benzamide

There total 5 articles about N-[(3-Phenyl-3-oxetanyl)methyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 93-97-0
benzoic acid anhydride

: 497239-45-9
(3-phenyloxetan-3-yl)methanamine

: 497239-46-0
N-(3-phenyloxetan-3-ylmethyl)benzamide

Guidance literature:: With triethylamine; In chloroform; at 20 ℃; for 4h;
DOI:10.1016/S0040-4020(02)00702-0

Reference yield:

: 4704-99-8
α,α,α-tris(hydroxymethyl)toluene

: 497239-46-0
N-(3-phenyloxetan-3-ylmethyl)benzamide

Guidance literature:: Multi-step reaction with 5 steps

1: 51 percent / diethyl carbonate; KOH / 5 h / 95 - 100 °C

2: 94 percent / aq. NaOH / tetrahydrofuran / 2.5 h / 20 °C

3: 58 percent / dimethylformamide / 2 h / 80 °C

4: 54 percent / hydrazine hydrate / ethanol / 3 h / Heating

5: 63 percent / Et₃N / CHCl₃ / 4 h / 20 °C

With potassium hydroxide; sodium hydroxide; hydrazine hydrate; triethylamine; Diethyl carbonate; In tetrahydrofuran; ethanol; chloroform; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(02)00702-0

Reference yield:

: 114012-43-0
(3-phenyl-oxetan-3-yl)methanol

: 497239-46-0
N-(3-phenyloxetan-3-ylmethyl)benzamide

Guidance literature:: Multi-step reaction with 4 steps

1: 94 percent / aq. NaOH / tetrahydrofuran / 2.5 h / 20 °C

2: 58 percent / dimethylformamide / 2 h / 80 °C

3: 54 percent / hydrazine hydrate / ethanol / 3 h / Heating

4: 63 percent / Et₃N / CHCl₃ / 4 h / 20 °C

With sodium hydroxide; hydrazine hydrate; triethylamine; In tetrahydrofuran; ethanol; chloroform; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(02)00702-0