Phosphonic acid, (1-hydroxy-1-phenylethyl)-

Base Information

• Chemical Name: Phosphonic acid, (1-hydroxy-1-phenylethyl)-
• CAS No.: 50655-82-8
• Molecular Formula: C8H11O4P
• Molecular Weight: 202.147
• DSSTox Substance ID: DTXSID10472153
• Mol file: 50655-82-8.mol

Synonyms:50655-82-8;Phosphonic acid, (1-hydroxy-1-phenylethyl)-;SCHEMBL7232658;DTXSID10472153

Chemical Property of Phosphonic acid, (1-hydroxy-1-phenylethyl)-

Chemical Property:

• XLogP3: -0.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 202.03949583
• Heavy Atom Count: 13
• Complexity: 218

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC=CC=C1)(O)P(=O)(O)O

Technology Process of Phosphonic acid, (1-hydroxy-1-phenylethyl)-

There total 10 articles about Phosphonic acid, (1-hydroxy-1-phenylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

acetic acid (64-19-7,77671-22-8) + acetophenone (98-86-2) → (1-hydroxy-1-phenylethyl)phosphonic acid (50655-82-8) + acetyl chloride (75-36-5)

Guidance literature:

acetophenone; With phosphorus trichloride; at 20 ℃; for 2h;

acetic acid; for 24h;

Reference yield: 80.0%

acetophenone (98-86-2) → (1-hydroxy-1-phenylethyl)phosphonic acid (50655-82-8)

Guidance literature:

With acetic acid; phosphorus trichloride;

Reference yield:

(1-chloro-1-phenylethyl)phosphonic acid (50655-83-9) → (1-hydroxy-1-phenylethyl)phosphonic acid (50655-82-8)

Guidance literature:

With water;

upstream raw materials:

(1-chloro-1-phenylethyl)phosphonic acid

(1-hydroxy-1-phenyl-ethyl)-phosphinic acid

C₁₇H₃₅O₄PSi₃

acetophenone

Downstream raw materials:

1-phenylvinylphosphonic acid

(1-chloro-1-phenylethyl)phosphonic acid