Ribavirin 2',3',5'-triacetate

Base Information

Chemical Name:Ribavirin 2',3',5'-triacetate
CAS No.:40372-03-0
Molecular Formula:C14H18N4O8
Molecular Weight:370.3147
Hs Code.:
European Community (EC) Number:806-551-0
DSSTox Substance ID:DTXSID10193356
Wikidata:Q76279771
Mol file:40372-03-0.mol

Synonyms:ribavirin 2',3',5'-triacetate

Suppliers and Price of Ribavirin 2',3',5'-triacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ribavirin2,3,5-Tri-O-acetyl
50mg
$ 155.00

Total 2 raw suppliers

Chemical Property of Ribavirin 2',3',5'-triacetate

Chemical Property:

Vapor Pressure:2.19E-12mmHg at 25°C
Boiling Point:555.6°Cat760mmHg
PKA:14.59±0.50(Predicted)
Flash Point:289.8°C
PSA：161.93000
Density:1.6g/cm³
LogP:-0.59880
XLogP3:-0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:9
Exact Mass:370.11246355
Heavy Atom Count:26
Complexity:585

Purity/Quality:

95% ^*data from raw suppliers

Ribavirin2,3,5-Tri-O-acetyl ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OCC1C(C(C(O1)N2C=NC(=N2)C(=O)N)OC(=O)C)OC(=O)C
Isomeric SMILES:CC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC(=N2)C(=O)N)OC(=O)C)OC(=O)C
Uses Protected Ribavirin (R414475), a purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.ribavirin 2',3',5'-triacetate is suitable for pyruvate dehydrogenase (PDH) related research.

Technology Process of Ribavirin 2',3',5'-triacetate

There total 2 articles about Ribavirin 2',3',5'-triacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 108-24-7
acetic anhydride

: 36791-04-5,66510-90-5
ribavirin

: 40372-03-0
2',3',5'-Tri-O-acetyl-1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide

Guidance literature:: With pyridine; at 20 ℃; for 22h; Concentration;

Reference yield:

: 40372-03-0
2',3',5'-Tri-O-acetyl-1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide

Guidance literature:: Aus 10;

Reference yield: 73.0%

: 40372-03-0
2',3',5'-Tri-O-acetyl-1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide

: 58151-87-4
5'-O-acetylribavirin

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; water; at 20 ℃; for 16h; regioselective reaction; Mechanism;
DOI:10.1002/ejoc.201400085