4-Benzoyl-1-methanesulphonylpiperidine

Base Information

Chemical Name:4-Benzoyl-1-methanesulphonylpiperidine
CAS No.:515154-31-1
Molecular Formula:C13H17NO3S
Molecular Weight:267.349
Hs Code.:
DSSTox Substance ID:DTXSID50581399
Nikkaji Number:J2.409.857E
Wikidata:Q82472530

Synonyms:4-benzoyl-1-methanesulphonylpiperidine;515154-31-1;SCHEMBL3595154;DTXSID50581399;IQLLFLWYARVSRO-UHFFFAOYSA-N;[1-(methylsulfonyl)-4-piperidinyl](phenyl)methanone;[1-(Methanesulfonyl)piperidin-4-yl](phenyl)methanone

Suppliers and Price of 4-Benzoyl-1-methanesulphonylpiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Benzoyl-1-methanesulphonylpiperidine

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:267.09291458
Heavy Atom Count:18
Complexity:385

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)N1CCC(CC1)C(=O)C2=CC=CC=C2

Technology Process of 4-Benzoyl-1-methanesulphonylpiperidine

There total 7 articles about 4-Benzoyl-1-methanesulphonylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 124-63-0
methanesulfonyl chloride

: 25519-80-6
4-(benzoyl)piperidine hydrochloride

: 515154-31-1
4-benzoyl-1-methanesulphonylpiperidine

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 25 ℃; for 16h;

Reference yield:

: (1-methanesulfonyl-piperidin-4-yl)-phenyl-methanol

: 515154-31-1
4-benzoyl-1-methanesulphonylpiperidine

Guidance literature:: With Celite; pyridinium chlorochromate; In dichloromethane; at 20 ℃;
DOI:10.1016/j.tetlet.2006.11.072

Reference yield:

: 217487-18-8
1-methanesulfonylpiperidine-4-carboxylic acid ethyl ester

: 515154-31-1
4-benzoyl-1-methanesulphonylpiperidine

Guidance literature:: Multi-step reaction with 4 steps

1: lithium aluminum hydride / tetrahydrofuran / 0 °C

2: pyridinium chlorochromate; Celite / CH₂Cl₂ / 20 °C

3: tetrahydrofuran / -78 °C

4: pyridinium chlorochromate; Celite / CH₂Cl₂ / 20 °C

With lithium aluminium tetrahydride; Celite; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; 3: Grignard addition;
DOI:10.1016/j.tetlet.2006.11.072