8-Methylene-1,4-dioxaspiro[4.5]decane

Base Information

• Chemical Name: 8-Methylene-1,4-dioxaspiro[4.5]decane
• CAS No.: 51656-90-7
• Molecular Formula: C9H14O2
• Molecular Weight: 154.209
• Hs Code.: 2932990090
• DSSTox Substance ID: DTXSID20449533
• Nikkaji Number: J1.584.746H
• Wikidata: Q82269040
• Mol file: 51656-90-7.mol

Synonyms:51656-90-7;8-Methylene-1,4-dioxaspiro[4.5]decane;8-methylidene-1,4-dioxaspiro[4.5]decane;1,4-Dioxaspiro[4.5]decane, 8-methylene-;8-METHYLENE-1,4-DIOXA-SPIRO[4.5]DECANE;MFCD07779440;SCHEMBL136964;SCHEMBL12373432;DTXSID20449533;BCWKBPCNPHCCQS-UHFFFAOYSA-N;BCA65690;AKOS006286385;PB42961;1,4-Dioxa-8-methylenespiro[4.5]decane;8-methylene 1,4-dioxaspiro[4,5]decane;8-methyene-1,4-dioxa-spiro[4.5]decane;BS-28653;SY243188;FT-0698515;A854129;J-519461

Chemical Property of 8-Methylene-1,4-dioxaspiro[4.5]decane

Chemical Property:

• Boiling Point: 221.4±40.0 °C(Predicted)
• PSA: 18.46000
• Density: 1.04±0.1 g/cm3(Predicted)
• LogP: 1.85970
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 154.099379685
• Heavy Atom Count: 11
• Complexity: 156

Purity/Quality:

97% ^*data from raw suppliers

8-Methylene-1,4-dioxaspiro[4.5]decane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=C1CCC2(CC1)OCCO2

Technology Process of 8-Methylene-1,4-dioxaspiro[4.5]decane

There total 10 articles about 8-Methylene-1,4-dioxaspiro[4.5]decane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cyclohexanedione monoethylene ketal (4746-97-8) + Methyltriphenylphosphonium bromide (1779-49-3) → 8-methylene-1,4-dioxaspiro[4.5]decane (51656-90-7)

Guidance literature:

With potassium tert-butylate; In benzene; at 25 ℃; for 1h;

DOI:10.1016/S0040-4020(98)00788-1

Reference yield: 99.3%

→ 8-methylene-1,4-dioxaspiro[4.5]decane (51656-90-7)

Guidance literature:

Reference yield: 90.0%

1-(tert-butyl)-5-(methylsulfonyl)-1H-tetrazole (873869-19-3) + cyclohexanedione monoethylene ketal (4746-97-8) → 8-methylene-1,4-dioxaspiro[4.5]decane (51656-90-7)

Guidance literature:

With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 - 20 ℃; for 16h;

DOI:10.1021/jo051693a

upstream raw materials:

cyclohexanedione monoethylene ketal

Methylenetriphenylphosphorane

Methyltriphenylphosphonium bromide

3,5-bis(trifluoromethyl)phenyl methyl sulfone

Downstream raw materials:

(1,4-dioxaspiro[4.5]dec-8-yl)methanol

1,4-dioxaspiro[4.5]decane-8-carbaldehyde

4-methylenecyclohexanone

spiro[2.5]octan-6-one