(S)-Methyl 1-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoyl)pyrrolidine-2-carboxylate

Base Information

Chemical Name:(S)-Methyl 1-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoyl)pyrrolidine-2-carboxylate
CAS No.:51827-14-6
Molecular Formula:C19H26N2O5
Molecular Weight:362.426
Hs Code.:
DSSTox Substance ID:DTXSID701192326

Synonyms:51827-14-6;(S)-Methyl 1-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoyl)pyrrolidine-2-carboxylate;Z-Val-Pro-OMe;SCHEMBL1506200;N-Cbz-valylproline methyl ester;BXFXOUDVGGJGQL-HOTGVXAUSA-N;DTXSID701192326;METHYL (2S)-1-[(2S)-2-{[(BENZYLOXY)CARBONYL]AMINO}-3-METHYLBUTANOYL]PYRROLIDINE-2-CARBOXYLATE;Benzyloxycarbonyl-L-valyl-L-proline methyl ester;N-[(Phenylmethoxy)carbonyl]-L-valyl-L-proline methyl ester;methyl (2S)-1-[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]pyrrolidine-2-carboxylate

Suppliers and Price of (S)-Methyl 1-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoyl)pyrrolidine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-Methyl 1-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoyl)pyrrolidine-2-carboxylate

Chemical Property:

PSA：84.94000
LogP:2.43020
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:362.18417193
Heavy Atom Count:26
Complexity:502

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)N1CCCC1C(=O)OC)NC(=O)OCC2=CC=CC=C2
Isomeric SMILES:CC(C)[C@@H](C(=O)N1CCC[C@H]1C(=O)OC)NC(=O)OCC2=CC=CC=C2

Technology Process of (S)-Methyl 1-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoyl)pyrrolidine-2-carboxylate

There total 11 articles about (S)-Methyl 1-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoyl)pyrrolidine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 2133-40-6
L-proline methyl ester monohydrochloride

: 51827-14-6
N-[(Phenylmethoxy)carbonyl]-L-valyl-L-proline methyl ester

Guidance literature:: With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1039/b617217b

Reference yield: 91.0%

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 2577-48-2
methyl (2S)-pyrrolidine carboxylate

: 51827-14-6
N-[(Phenylmethoxy)carbonyl]-L-valyl-L-proline methyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; for 0.5h;