1-Bromo-2-(3-indenyl)ethane

Base Information

• Chemical Name: 1-Bromo-2-(3-indenyl)ethane
• CAS No.: 52001-48-6
• Molecular Formula: C11H11Br
• Molecular Weight: 223.112
• DSSTox Substance ID: DTXSID20479315
• Nikkaji Number: J2.139.206E
• Wikidata: Q82313300
• Mol file: 52001-48-6.mol

Synonyms:1-bromo-2-(3-indenyl)ethane;52001-48-6;3-(2-bromoethyl)indene;SCHEMBL1822774;DTXSID20479315;KKZPDPNTMKHMNU-UHFFFAOYSA-N;2-(1H-inden-3-yl)-1-bromoethane

Chemical Property of 1-Bromo-2-(3-indenyl)ethane

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 222.00441
• Heavy Atom Count: 12
• Complexity: 183

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1C=C(C2=CC=CC=C21)CCBr

Technology Process of 1-Bromo-2-(3-indenyl)ethane

There total 1 articles about 1-Bromo-2-(3-indenyl)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

ethylene dibromide (106-93-4) + 1-indene (95-13-6) → 1-(2'bromoethyl)-1H-indene (65056-65-7) + spiro(cyclopropane-1,1'-<1H>-indene) (19770-38-8) + 1,2-bis(1H-inden-3-yl)ethane (18657-57-3) + 3-(2'-bromoethyl)-1H-indene (52001-48-6)

Guidance literature:

1-indene; With n-butyllithium; In tetrahydrofuran; at 0 ℃;

ethylene dibromide; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.tetlet.2004.12.101

Reference yield: 64.0%

N1-(2,6-diisopropylphenyl)ethane-1,2-diamine (888705-44-0) + 3-(2'-bromoethyl)-1H-indene (52001-48-6) → C25H34N2

Guidance literature:

In neat (no solvent); at 100 ℃; for 3h; Sealed tube;

DOI:10.1039/c5dt04060d

Reference yield:

3-(2'-bromoethyl)-1H-indene (52001-48-6) + N-(piperidin-4-yl)benzamide (33953-37-6) → 1-[2-(3-Indenyl)ethyl]-4-benzamidopiperidine (36793-43-8)

Guidance literature:

With potassium carbonate; In isopropyl alcohol;

upstream raw materials:

ethylene dibromide

1-indene

Downstream raw materials:

1-[2-(3-Indenyl)ethyl]-4-benzamidopiperidine