3-Amino-2-hydroxybenzyl alcohol

Base Information

• Chemical Name: 3-Amino-2-hydroxybenzyl alcohol
• CAS No.: 52820-13-0
• Molecular Formula: C7H9NO2
• Molecular Weight: 139.154
• Mol file: 52820-13-0.mol

Synonyms:42017 2-AMINO-4-(HYDROXYMETHYL)PHENOL;4-hydroxymethyl-2-aminophenol;2-Amino-4-hydroxymethyl-phenol;3-amino-4-hydroxy-benzyl alcohol;2-amino-4-(hydroxymethyl)phenol;3-Amino-4-hydroxy-benzylalkohol;2-amino-4-hydroxymethylphenol;

Chemical Property of 3-Amino-2-hydroxybenzyl alcohol

Chemical Property:

• PSA: 66.48000
• LogP: 1.04790

Purity/Quality:

98% ^*data from raw suppliers

2-Amino-4-(hydroxymethyl)phenol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Amino-2-hydroxybenzyl alcohol

There total 5 articles about 3-Amino-2-hydroxybenzyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

→ 3-Amino-4-hydroxybenzyl alcohol (52820-13-0)

Guidance literature:

Reference yield: 60.0%

4-hydroxymethyl-2-nitrophenol (41833-13-0) → 3-Amino-4-hydroxybenzyl alcohol (52820-13-0)

Guidance literature:

palladium; In ethanol;

Reference yield: 41.0%

4-hydroxy-3-nitrobenzaldehyde (3011-34-5) → 3-Amino-4-hydroxybenzyl alcohol (52820-13-0) + 3-amino-4-hydroxytoluene (95-84-1)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethanol; for 4h; under 1551.49 Torr;

DOI:10.1016/j.bmc.2012.01.021

upstream raw materials:

4-hydroxymethyl-2-nitrophenol

4-hydroxy-3-nitrobenzaldehyde

Downstream raw materials:

<(S)-(benzyloxycarbonyl)-L-valyl>-N-<1-<<5-<<(tert-butyldimethylsilyl)oxy>methyl>benzoxazol-2-yl>carbonyl>-2-methylpropyl>-L-prolinamide

(3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-methanol

michigazone

Refernces

• 1、 Prasain, Keshar,Nguyen, Thi D.T.,Gorman, Maureen J.,Barrigan, Lydia M.,Peng, Zeyu,Kanost, Michael R.,Syed, Lateef U.,Li, Jun,Zhu, Kun Yan,Hua, Duy H.. "Redox potentials, laccase oxidation, and antilarval activities of substituted phenols". experimental part. p. 1679 - 1689. Retrieved 2012/04/23.
• 2、 Bouvier, Emmanuel,Thirot, Sylvie,Schmidt, Frederic,Monneret, Claude. "First enzymatically activated Taxotere prodrugs designed for ADEPT and PMT". . p. 969 - 977. Retrieved 2007/10/03.