3-(2-Hydroxyethyl)pentane-1,5-diol

Base Information

Chemical Name:3-(2-Hydroxyethyl)pentane-1,5-diol
CAS No.:53378-75-9
Molecular Formula:C7H16O3
Molecular Weight:148.202
Hs Code.:
DSSTox Substance ID:DTXSID60476560
Wikidata:Q82308053
Mol file:53378-75-9.mol

Synonyms:3-(2-hydroxyethyl)pentane-1,5-diol;53378-75-9;tris(2hydroxyethyl)methane;1,5-Pentanediol, 3-(2-hydroxyethyl)-;tris(2-hydroxyethyl)methane;tri(2-hydroxyethyl)methane;SCHEMBL63049;DTXSID60476560;ZICHXHRTBFGJFH-UHFFFAOYSA-N

Suppliers and Price of 3-(2-Hydroxyethyl)pentane-1,5-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-(2-Hydroxyethyl)pentane-1,5-diol

Chemical Property:

Boiling Point:189-191 °C(Press: 2 Torr)
PSA：60.69000
Density:1.087 g/cm3(Temp: 19 °C)
LogP:-0.25020
XLogP3:-0.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:148.109944368
Heavy Atom Count:10
Complexity:51.6

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CO)C(CCO)CCO

Technology Process of 3-(2-Hydroxyethyl)pentane-1,5-diol

There total 1 articles about 3-(2-Hydroxyethyl)pentane-1,5-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.1%

: 87986-82-1
tris(2-acetoxyethyl)methane

: 60-35-5
acetamide

: 53378-75-9
3-(2-hydroxyethyl)pentane-1,5-diol

Guidance literature:: tris(2-acetoxyethyl)methane; With ammonia; In methanol; at 80 ℃; for 96h;

With ammonia; at 80 ℃; for 24h;

Reference yield:

: 53378-75-9
3-(2-hydroxyethyl)pentane-1,5-diol

: 100-76-5
Quinuclidine

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; hydrogen bromide

2: methanol; NH₃ / 140 °C

With methanol; ammonia; hydrogen bromide; acetic acid;

Reference yield:

: 53378-75-9
3-(2-hydroxyethyl)pentane-1,5-diol

: 489427-21-6
4-{5-(2-hydroxyimino-1,1-dimethyl-propylamino)-3-[2-(2-hydroxyimino-1,1-dimethyl-propylamino)-ethyl]-pentylcarbamoyl}-thiobutyric acid 2,3,5,6-tetrafluoro-phenyl ester

Guidance literature:: Multi-step reaction with 6 steps

1.1: pyridine / dichloromethane / 24 h / 15 - 20 °C / Inert atmosphere

2.1: sodium azide / N,N-dimethyl-formamide / 24.5 h / 50 °C / Inert atmosphere; Cooling with ice

3.1: palladium 10% on activated carbon; hydrogen / water; ethanol / 12 h

4.1: potassium carbonate / ethanol / 20 °C / Inert atmosphere

5.1: N,N-dimethyl-formamide / 23 h

6.1: HATU; 4-methyl-morpholine / N,N-dimethyl-formamide / 0.08 h

6.2: 0.17 h

With 4-methyl-morpholine; pyridine; sodium azide; palladium 10% on activated carbon; hydrogen; potassium carbonate; HATU; In ethanol; dichloromethane; water; N,N-dimethyl-formamide;