N-Vanillylacetamide

Base Information

Chemical Name:N-Vanillylacetamide
CAS No.:53527-04-1
Molecular Formula:C10H13NO3
Molecular Weight:195.218
Hs Code.:2924299090
Mol file:53527-04-1.mol

Synonyms:N-(4-hydroxy-3-methoxybenzyl)acetamide;N-Vanillyl-acetamid;2-Methoxy-4-acetaminomethyl-phenol;N-(4-Oxy-3-methoxy-benzyl)-acetamid;N-vanillyl-acetamide;Essigsaeure-(4-oxy-3-methoxy-benzylamid);Acetamide,N-[(4-hydroxy-3-methoxyphenyl)methyl];

Suppliers and Price of N-Vanillylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[(4-hydroxy-3-methoxyphenyl)methyl]acetamide
50mg
$ 45.00

Total 1 raw suppliers

Chemical Property of N-Vanillylacetamide

Chemical Property:

Melting Point:82-83 °C
Boiling Point:435.6±35.0 °C(Predicted)
PKA:10.02±0.31(Predicted)
PSA：62.05000
Density:1.168±0.06 g/cm3(Predicted)
LogP:1.87720

Purity/Quality:: N-[(4-hydroxy-3-methoxyphenyl)methyl]acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-Vanillylacetamide

There total 10 articles about N-Vanillylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1196-92-5
Vanillylamin

: 64-17-5
ethanol

: 53527-04-1
N-(4-hydroxy-3-methoxybenzyl)acetamide

Guidance literature:: With indium(III) chloride; oxygen; ferric nitrate; at 30 ℃; for 0.5h; Schlenk technique;

Reference yield: 58.0%

: 108-24-7
acetic anhydride

: 7149-10-2
vanillylamine hydrochloride

: 53527-04-1
N-(4-hydroxy-3-methoxybenzyl)acetamide

Guidance literature:: With sodium acetate; at 130 ℃; for 6h;
DOI:10.1021/jo034616t

Reference yield: 48.35%

: 7149-10-2
vanillylamine hydrochloride

: 75-36-5
acetyl chloride

: 53527-04-1
N-(4-hydroxy-3-methoxybenzyl)acetamide

Guidance literature:: vanillylamine hydrochloride; With sodium hydroxide; In water; N,N-dimethyl-formamide; at 20 ℃; for 1h; Inert atmosphere; Cooling with ice;

acetyl chloride; In tetrahydrofuran; water; N,N-dimethyl-formamide; at 20 ℃; for 18h; Inert atmosphere; Cooling with ice;
DOI:10.1021/jf9035029