N-(2-(1H-Indol-3-yl)ethyl)-N-methylformamide

Base Information

Chemical Name:N-(2-(1H-Indol-3-yl)ethyl)-N-methylformamide
CAS No.:54268-27-8
Molecular Formula:C12H14N2O
Molecular Weight:202.256
Hs Code.:
DSSTox Substance ID:DTXSID30565894
Nikkaji Number:J2.201.519B
Wikidata:Q82451222

Synonyms:N-(2-(1H-Indol-3-yl)ethyl)-N-methylformamide;54268-27-8;N-[2-(1H-Indol-3-yl)ethyl]-N-methylformamide;DTXSID30565894;CS-0042237

Suppliers and Price of N-(2-(1H-Indol-3-yl)ethyl)-N-methylformamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
N-(2-(1H-Indol-3-yl)ethyl)-N-methylformamide 95%+
100mg
$ 675.00

Chemenu
N-(2-(1H-Indol-3-yl)ethyl)-N-methylformamide 95%+
250mg
$ 621.00

Total 3 raw suppliers

Chemical Property of N-(2-(1H-Indol-3-yl)ethyl)-N-methylformamide

Chemical Property:

PSA：36.10000
LogP:2.43450
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:202.110613074
Heavy Atom Count:15
Complexity:220

Purity/Quality:

NLT 98% ^*data from raw suppliers

N-(2-(1H-Indol-3-yl)ethyl)-N-methylformamide 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(CCC1=CNC2=CC=CC=C21)C=O

Technology Process of N-(2-(1H-Indol-3-yl)ethyl)-N-methylformamide

There total 9 articles about N-(2-(1H-Indol-3-yl)ethyl)-N-methylformamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 64-18-6
formic acid

: 61-49-4
[2-(1H-indol-3-yl)-ethyl]-methylamine

: 54268-27-8
N^b-formyl-N^b-methyltryptamine

Guidance literature:: formic acid; With acetic anhydride; at 60 ℃; for 1h;

[2-(1H-indol-3-yl)-ethyl]-methylamine; In dichloromethane; at 20 ℃; for 1.5h;
DOI:10.1021/ol0627348

Reference yield: 40.0%

: 61-49-4
[2-(1H-indol-3-yl)-ethyl]-methylamine

: 201230-82-2
carbon monoxide

: 54268-27-8
N^b-formyl-N^b-methyltryptamine

: 59156-98-8
Strychnocarpine

Guidance literature:: With oxygen; copper diacetate; palladium diacetate; In toluene; at 80 ℃; for 6h; under 760.051 Torr; Schlenk technique;
DOI:10.1021/acs.joc.8b03266

Reference yield:

: 120-72-9
indole

: 54268-27-8
N^b-formyl-N^b-methyltryptamine

: 59156-98-8
Strychnocarpine

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 0 - 20 °C

1.2: 2 h / 0 - 20 °C

1.3: 4 h / Reflux

2.1: copper diacetate; palladium diacetate; oxygen / toluene / 6 h / 80 °C / 760.05 Torr / Schlenk technique

With oxygen; copper diacetate; palladium diacetate; In tetrahydrofuran; toluene;
DOI:10.1021/acs.joc.8b03266