Technology Process of diethyl (2R,3R)-2-benzyl-3-hydroxyglutarate
There total 3 articles about diethyl (2R,3R)-2-benzyl-3-hydroxyglutarate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
D-glucose; NADPH; sodium chloride;
lyophilized glucose dehydrogenase; NADPH-dependent ketoreductase KRED-108;
In
phosphate buffer; dimethyl sulfoxide;
at 37 ℃;
pH=6.5;
Enzymatic reaction;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium diisopropylamine / hexane; tetrahydrofuran / 0.17 h / -18 °C
1.2: tetrahydrofuran; hexane / 4.5 h / -18 - 20 °C
2.1: 97 percent Chromat. / glucose; NaCl; NADPH / NADPH-dependent ketoreductase KRED-108; lyophilized glucose dehydrogenase / aq. phosphate buffer; dimethylsulfoxide / 37 °C / pH 6.5 / Enzymatic reaction
With
D-glucose; NADPH; sodium chloride; lithium diisopropyl amide;
lyophilized glucose dehydrogenase; NADPH-dependent ketoreductase KRED-108;
In
tetrahydrofuran; phosphate buffer; hexane; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium diisopropylamine / hexane; tetrahydrofuran / 0.17 h / -18 °C
1.2: tetrahydrofuran; hexane / 4.5 h / -18 - 20 °C
2.1: 97 percent Chromat. / glucose; NaCl; NADPH / NADPH-dependent ketoreductase KRED-108; lyophilized glucose dehydrogenase / aq. phosphate buffer; dimethylsulfoxide / 37 °C / pH 6.5 / Enzymatic reaction
With
D-glucose; NADPH; sodium chloride; lithium diisopropyl amide;
lyophilized glucose dehydrogenase; NADPH-dependent ketoreductase KRED-108;
In
tetrahydrofuran; phosphate buffer; hexane; dimethyl sulfoxide;
