2-Bromo-4,5-dimethoxybenzoyl chloride

Base Information

• Chemical Name: 2-Bromo-4,5-dimethoxybenzoyl chloride
• CAS No.: 55171-61-4
• Molecular Formula: C9H8BrClO3
• Molecular Weight: 279.518
• Hs Code.: 2918990090
• DSSTox Substance ID: DTXSID30451021
• Wikidata: Q82270875
• Mol file: 55171-61-4.mol

Synonyms:2-BROMO-4,5-DIMETHOXYBENZOYL CHLORIDE;55171-61-4;SCHEMBL7970746;DTXSID30451021;BBL037147;MFCD12025332;STL508830;AKOS005173103;VS-13940;FT-0745333

Chemical Property of 2-Bromo-4,5-dimethoxybenzoyl chloride

Chemical Property:

• Boiling Point: 341.7±37.0 °C(Predicted)
• PSA: 35.53000
• Density: 1.552±0.06 g/cm3(Predicted)
• LogP: 2.84530
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 277.93453
• Heavy Atom Count: 14
• Complexity: 212

Purity/Quality:

98%min ^*data from raw suppliers

2-Bromo-4,5-dimethoxybenzoyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C(=C1)C(=O)Cl)Br)OC

Technology Process of 2-Bromo-4,5-dimethoxybenzoyl chloride

There total 3 articles about 2-Bromo-4,5-dimethoxybenzoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-bromo-4,5-dimethoxybenzoic acid (6286-46-0) → 2-bromo-4,5-dimethoxybenzoyl chloride (55171-61-4)

Guidance literature:

With thionyl chloride; for 3h; Reflux;

Reference yield:

2-bromo-4,5-dimethoxybenzaldehyde (5392-10-9) → 2-bromo-4,5-dimethoxybenzoyl chloride (55171-61-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / KMnO₄ / H₂O; acetone / 1 h / Heating

2: SOCl₂ / CHCl₃ / 1 h / Heating

With potassium permanganate; thionyl chloride; In chloroform; water; acetone;

Reference yield:

→ 2-bromo-4,5-dimethoxybenzoyl chloride (55171-61-4)

Guidance literature:

upstream raw materials:

2-bromo-4,5-dimethoxybenzoic acid

2-bromo-4,5-dimethoxybenzaldehyde

Downstream raw materials:

2-(2-bromo-4,5-dimethoxy-benzoyl)-6,7-dimethoxy-1-methylene-1,2,3,4-tetrahydro-isoquinoline

2-(2-bromo-4,5-dimethoxybenzoyl)-1-ethylidene-1,2,3,4-tetrahydro-6,7-dimethoxy-isoquinoline

2'-bromo-4',5'-dimethoxybenzoic acid 2-isopropoxy-3-methoxy-5-naphthylamide

2-Bromo-N-hydroxy-4,5-dimethoxy-N-phenyl-benzamide