potassium;N-hydroxy-4-methoxybenzamide

Base Information

• Chemical Name: potassium;N-hydroxy-4-methoxybenzamide
• CAS No.: 57139-22-7
• Molecular Formula: C8H9NO3
• Molecular Weight: 205.255
• NSC Number: 196145
• Mol file: 57139-22-7.mol

Synonyms:NSC196145;NSC-196145;57139-22-7

Chemical Property of potassium;N-hydroxy-4-methoxybenzamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.24g/cm³
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 206.02194963
• Heavy Atom Count: 13
• Complexity: 152

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(=O)NO.[K+]

Technology Process of potassium;N-hydroxy-4-methoxybenzamide

There total 4 articles about potassium;N-hydroxy-4-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

ethyl 4-methoxybenzoate (94-30-4) → potassium p-methoxylbenzohydroxamate (57139-22-7)

Guidance literature:

With potassium hydroxide; hydroxylamine hydrochloride; In methanol;

Reference yield:

4-methoxybenzoic acid (100-09-4) → potassium p-methoxylbenzohydroxamate (57139-22-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / Reflux

2: hydroxylamine hydrochloride; potassium hydroxide / methanol

With sulfuric acid; hydroxylamine hydrochloride; potassium hydroxide; In methanol; 1: |Fischer-Speier Esterification;

DOI:10.14233/ajchem.2019.21621

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → potassium p-methoxylbenzohydroxamate (57139-22-7)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium permanganate; sodium hydroxide / water / 0.3 h / 20 °C / Reflux

2: sulfuric acid / Reflux

3: hydroxylamine hydrochloride; potassium hydroxide / methanol

With potassium permanganate; sulfuric acid; hydroxylamine hydrochloride; potassium hydroxide; sodium hydroxide; In methanol; water; 2: |Fischer-Speier Esterification;

DOI:10.14233/ajchem.2019.21621

upstream raw materials:

ethyl 4-methoxybenzoate

4-methoxybenzoic acid

4-methoxy-benzaldehyde

Downstream raw materials:

butyl p-methoxybenzohydroxamate

N-p-methoxybenzoyl-O-benzylhydroxylamine

N-<4-Methoxy-benzoyl>-O-propyl-hydroxylamin

N-<4-Methoxy-benzoyl>-O-propargyl-hydroxylamin