N-hydroxy-4-methoxybenzamide

Base Information

• Chemical Name: N-hydroxy-4-methoxybenzamide
• CAS No.: 10507-69-4
• Molecular Formula: C8H9 N O3
• Molecular Weight: 167.164
• Hs Code.: 2924299090
• Mol file: 10507-69-4.mol

Synonyms:p-Anisohydroxamicacid (6CI,7CI,8CI); 4-Methoxybenzenehydroxamic acid; 4-Methoxybenzohydroxamicacid; 4-Methoxyphenylhydroxamic acid; N-Hydroxy-4-methoxybenzamide; NSC 5096;NSC 682752; p-Methoxybenzohydroxamic acid; p-Methoxyphenylhydroxamic acid

Chemical Property of N-hydroxy-4-methoxybenzamide

Chemical Property:

• PSA: 58.56000
• Density: 1.24g/cm³
• LogP: 1.20510

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-hydroxy-4-methoxybenzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-hydroxy-4-methoxybenzamide can be used as anti-HCV agents, as well as, inhibitors of urease.

Technology Process of N-hydroxy-4-methoxybenzamide

There total 25 articles about N-hydroxy-4-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-methoxy-benzoyl chloride (100-07-2) → 4-methoxybenzohydroxamic acid (10507-69-4)

Guidance literature:

With hydroxylamine hydrochloride; sodium hydrogencarbonate; In water; ethyl acetate; at 20 ℃; for 0.0833333h;

DOI:10.1007/s00775-020-01755-6

Reference yield: 98.0%

4-methoxy-benzaldehyde (123-11-5) → 4-methoxybenzohydroxamic acid (10507-69-4)

Guidance literature:

With polymer-bound N-hydroxybenzenesulfonamide; sodium methylate; In tetrahydrofuran; methanol; at 20 ℃; for 7h;

DOI:10.1021/jo061018g

Reference yield: 88.0%

4-methoxybenzoic acid (100-09-4) → 4-methoxybenzohydroxamic acid (10507-69-4)

Guidance literature:

With N-Bromosuccinimide; hydroxylamine hydrochloride; triphenylphosphine; In triethylamine; acetonitrile; at 20 ℃; for 2h;

DOI:10.1002/jccs.200000140

upstream raw materials:

ethyl 4-methoxybenzoate

piloty's acid

4-methoxy-benzaldehyde

4-methoxy-benzoyl chloride

Downstream raw materials:

O-benzoyl-N-(4-methoxy-benzoyl)-hydroxylamine

4-methoxy-aniline

4-methoxyformanilide

4-Methoxyphenyl isocyanate