2,3-Furandione, 5-(4-bromophenyl)-

Base Information

• Chemical Name: 2,3-Furandione, 5-(4-bromophenyl)-
• CAS No.: 55991-70-3
• Molecular Formula: C10H5BrO3
• Molecular Weight: 253.052
• DSSTox Substance ID: DTXSID90481586
• Nikkaji Number: J500.527B
• Wikidata: Q82317072
• Mol file: 55991-70-3.mol

Synonyms:2,3-Furandione, 5-(4-bromophenyl)-;55991-70-3;DTXSID90481586;5-(p-bromophenyl)-furan-2,3-dione;AKOS005224824;5-(4-Bromo-phenyl)-furan-2,3-dione

Chemical Property of 2,3-Furandione, 5-(4-bromophenyl)-

Chemical Property:

• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 251.94221
• Heavy Atom Count: 14
• Complexity: 301

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC=C1C2=CC(=O)C(=O)O2)Br

Technology Process of 2,3-Furandione, 5-(4-bromophenyl)-

There total 5 articles about 2,3-Furandione, 5-(4-bromophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-(4-bromo-phenyl)-2,4-dioxo-butyric acid (58303-63-2) → 5-(4-bromo-phenyl)-furan-2,3-dione (55991-70-3)

Guidance literature:

With acetic anhydride; at 60 - 70 ℃;

DOI:10.1007/BF02251994

Reference yield: 80.0%

oxalyl dichloride (79-37-8) + 1-(4-bromophenyl)-1-(trimethylsilyloxy)ethylene (55991-66-7) → 5-(4-bromo-phenyl)-furan-2,3-dione (55991-70-3)

Guidance literature:

In diethyl ether; for 5h; Ambient temperature;

Reference yield:

para-bromoacetophenone (99-90-1) → 5-(4-bromo-phenyl)-furan-2,3-dione (55991-70-3)

Guidance literature:

Multi-step reaction with 2 steps

1: Na / methanol; diethyl ether

2: AcCl / Heating

With sodium; acetyl chloride; In methanol; diethyl ether;

DOI:10.1023/A:1012438902959

upstream raw materials:

oxalyl dichloride

1-(4-bromophenyl)-1-(trimethylsilyloxy)ethylene

4-(4-bromo-phenyl)-2,4-dioxo-butyric acid

(Z)-4-(4-bromophenyl)-2-hydroxy-4-oxobut-2-enoic acid

Downstream raw materials:

[5-(4-Bromo-phenyl)-3-oxo-3H-furan-(2Z)-ylidene]-acetic acid methyl ester

4-(4-Bromo-phenyl)-N-(cyano-dimethyl-methyl)-2,4-dioxo-butyramide

N-[3-(4-Bromo-phenyl)-3-oxo-propionyl]-2-cyano-acetamide

[5-(4-Bromo-phenyl)-2-hydroxy-3-oxo-2,3-dihydro-furan-2-yl]-acetic acid methyl ester