Pepper acid ethyl este

Base Information

• Chemical Name: Pepper acid ethyl este
• CAS No.: 56019-71-7
• Molecular Formula: C₁₄H₁₄O₄
• Molecular Weight: 246.263
• Mol file: 56019-71-7.mol

Synonyms:(2E,4E)-ethyl 5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienoate;Piperinsaeureaethylester;5t-benzo[1,3]dioxol-5-yl-penta-2t,4-dienoic acid ethyl ester;ethyl 5-(3,4-methylenedioxyphenyl)-2,4-pentadienoate;5t-Benzo[1,3]dioxol-5-yl-penta-2t,4-diensaeure-aethylester;

Chemical Property of Pepper acid ethyl este

Chemical Property:

• Melting Point: 76-77℃ (ethyl ether hexane )
• PSA: 44.76000
• LogP: 2.54780

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pepper acid ethyl este

There total 13 articles about Pepper acid ethyl este which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

(E)-4-[(diethoxyphosphinyl)oxy]-2-butenoic acid ethyl ester + piperonal (120-57-0,30024-74-9) → all-trans-5-(3,4-Methylendioxyphenyl)-2,4-pentadiensaeureethylester (6091-43-6,56019-71-7,60578-08-7,60578-12-3,63657-07-8)

Guidance literature:

(E)-4-[(diethoxyphosphinyl)oxy]-2-butenoic acid ethyl ester; With sodium hydride; In N,N-dimethyl-formamide; at 30 - 35 ℃; for 4h;

piperonal; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield: 86.0%

piperonal (120-57-0,30024-74-9) + ethyl (2E)-4-(diethoxyphosphoryl)crotonate (42516-28-9) → all-trans-5-(3,4-Methylendioxyphenyl)-2,4-pentadiensaeureethylester (6091-43-6,56019-71-7,60578-08-7,60578-12-3,63657-07-8)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; for 24h; Molecular sieve; Inert atmosphere; Reflux;

DOI:10.1016/j.bmc.2013.07.010

Reference yield: 67.0%

ethanol (64-17-5) + N-piperoyl-2-piperidone → all-trans-5-(3,4-Methylendioxyphenyl)-2,4-pentadiensaeureethylester (6091-43-6,56019-71-7,60578-08-7,60578-12-3,63657-07-8)

Guidance literature:

With triethylamine; at 85 ℃; for 4.5h;

DOI:10.1002/ejoc.201900517

upstream raw materials:

piperic acid

piperonal

ethyl (E)-crotonate

ethanol

Downstream raw materials:

piperic acid

5-(3',4'-methylenedioxyphenyl)pentanoic acid

piperlonguminine