2-Bromo-3-chloro-4-hydroxy-5-methoxybenzaldehyde

Base Information

• Chemical Name: 2-Bromo-3-chloro-4-hydroxy-5-methoxybenzaldehyde
• CAS No.: 90004-83-4
• Molecular Formula: C8H6BrClO3
• Molecular Weight: 265.4884
• Hs Code.: 2913000090
• NSC Number: 95791
• DSSTox Substance ID: DTXSID10294312
• Wikidata: Q82033548
• Mol file: 90004-83-4.mol

Synonyms:2-bromo-3-chloro-4-hydroxy-5-methoxybenzaldehyde;90004-83-4;CHEMBRDG-BB 6488232;NSC95791;6-bromo-5-chlorovanillin;SCHEMBL9016537;DTXSID10294312;HQOHSCYWUXNDDY-UHFFFAOYSA-N;MFCD04208551;NSC-95791;AKOS000104088;CS-0118909;SR-01000235735;SR-01000235735-1;2-Bromo-3-chloro-4-hydroxy-5-methoxybenzaldehyde, AldrichCPR

Chemical Property of 2-Bromo-3-chloro-4-hydroxy-5-methoxybenzaldehyde

Chemical Property:

• Vapor Pressure: 6.11E-05mmHg at 25°C
• Boiling Point: 335.6°Cat760mmHg
• Flash Point: 156.7°C
• PSA: 46.53000
• Density: 1.75g/cm³
• LogP: 2.62920
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 263.91888
• Heavy Atom Count: 13
• Complexity: 190

Purity/Quality:

2-bromo-3-chloro-4-hydroxy-5-methoxybenzaldehyde 95% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C(=C(C(=C1)C=O)Br)Cl)O

Technology Process of 2-Bromo-3-chloro-4-hydroxy-5-methoxybenzaldehyde

There total 2 articles about 2-Bromo-3-chloro-4-hydroxy-5-methoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-bromovanillin (60632-40-8) → 2-bromo-3-chloro-4-hydroxy-5-methoxy-benzaldehyde (90004-83-4)

Guidance literature:

With chloroform; chlorine; at 40 ℃;

DOI:10.1021/ja01374a061

Reference yield:

chloroform (67-66-3,8013-54-5) + 6-bromovanillin (60632-40-8) + chlorine (7782-50-5) → 2-bromo-3-chloro-4-hydroxy-5-methoxy-benzaldehyde (90004-83-4)

Guidance literature:

at 40 ℃;

DOI:10.1021/ja01374a061

Reference yield:

2-bromo-3-chloro-4-hydroxy-5-methoxy-benzaldehyde (90004-83-4) → 2-bromo-3-chloro-4-hydroxy-5-methoxy-benzaldehyde-oxime

Guidance literature:

DOI:10.1021/ja01331a062

upstream raw materials:

6-bromovanillin

chloroform

chlorine

Downstream raw materials:

2-bromo-3-chloro-4,5-dimethoxy-benzaldehyde