3-Methoxycinnamaldehyde

Base Information

• Chemical Name: 3-Methoxycinnamaldehyde
• CAS No.: 56578-36-0
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• Hs Code.: 2912499000
• Mol file: 56578-36-0.mol

Synonyms:3-Methoxycinnamaldehyde;m-Methoxyzimtaldehyd;3-Methoxy-zimtaldehyd;3-CH3OC6H4CHCHCHO;meta-methoxycinnamaldehyde;

Chemical Property of 3-Methoxycinnamaldehyde

Chemical Property:

• Vapor Pressure: 0.00145mmHg at 25°C
• Boiling Point: 296.3oC at 760 mmHg
• Flash Point: 137.8oC
• PSA: 26.30000
• Density: 1.068g/cm3
• LogP: 1.90730

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Methoxycinnamaldehyde

There total 37 articles about 3-Methoxycinnamaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(E)-3-(3-hydroxyphenyl)acrylaldehyde (26231-89-0) + methyl iodide (74-88-4) → (E)-m-methoxycinnamaldehyde (56578-36-0)

Guidance literature:

With potassium carbonate; In acetone; at 0 - 20 ℃;

DOI:10.1016/j.bmcl.2014.04.105

Reference yield: 95.0%

(E)-3-(3-Methoxyphenyl)-2-propen-1-ol (125617-35-8) → (E)-m-methoxycinnamaldehyde (56578-36-0)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 0 - 20 ℃; for 2h; Inert atmosphere;

Reference yield: 92.0%

(E)-1-(buta-1,3-dien-1-yl)-3-methoxybenzene (32507-40-7) → (E)-m-methoxycinnamaldehyde (56578-36-0)

Guidance literature:

With iron(III) sulfate hydrate; oxygen; In water; acetonitrile; at 45 ℃; for 18h; regioselective reaction;

DOI:10.1021/acs.orglett.9b03562

upstream raw materials:

(E)-3-methoxycinnamoyl chloride

3,3-Diethoxy-1-(3-methoxy-phenyl)-propan-1-one

(E)-1-methoxy-3-(prop-1-en-1-yl)benzene

acrylaldehyde diethyl acetal

Downstream raw materials:

(E)-1-(buta-1,3-dien-1-yl)-3-methoxybenzene

2-bromo-3-(3-methoxyphenyl)-2-propenal

6-methoxy-1-naphthalenecarboxylic acid methyl ester

(2E,4E)-2-Methoxy-5-(3-methoxy-phenyl)-penta-2,4-dienoic acid methyl ester