N-(2-hydroxyethyl)-N-methylbenzamide

Base Information

Chemical Name:N-(2-hydroxyethyl)-N-methylbenzamide
CAS No.:57440-15-0
Molecular Formula:C10H13NO2
Molecular Weight:179.219
Hs Code.:
DSSTox Substance ID:DTXSID90398746
Nikkaji Number:J1.346.868K
Wikidata:Q82200888

Synonyms:N-(2-hydroxyethyl)-N-methylbenzamide;57440-15-0;N-methyl-N-(2-hydroxyethyl)benzamide;SCHEMBL1004454;DTXSID90398746;NRERZMANNBLBLG-UHFFFAOYSA-N;2-(N-Benzoyl-N-methylamino)ethanol;AKOS008973145

Suppliers and Price of N-(2-hydroxyethyl)-N-methylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-(2-hydroxyethyl)-N-methylbenzamide

Chemical Property:

XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:164

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(CCO)C(=O)C1=CC=CC=C1

Technology Process of N-(2-hydroxyethyl)-N-methylbenzamide

There total 9 articles about N-(2-hydroxyethyl)-N-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 109-83-1
(2-hydroxyethyl)(methyl)amine

: 98-88-4
benzoyl chloride

: 57440-15-0
N-methyl-N-(2-hydroxyethyl)benzamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/acs.joc.1c02318

Reference yield: 90.0%

: 109-83-1
(2-hydroxyethyl)(methyl)amine

: 93-58-3,5705-52-2,80226-58-0
benzoic acid methyl ester

: 57440-15-0
N-methyl-N-(2-hydroxyethyl)benzamide

Guidance literature:: With dmap; oxo[hexa(trifluoroacetato)]tetrazinc; at 100 ℃; for 18h; Inert atmosphere;
DOI:10.1002/ejoc.201700748

Reference yield:

: 33757-48-1
N-quinolin-8-yl-benzamide

: 57440-15-0
N-methyl-N-(2-hydroxyethyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride; zinc trifluoromethanesulfonate; Diethyl carbonate / mineral oil / 18 h / Reflux

2: oxo[hexa(trifluoroacetato)]tetrazinc; dmap / 18 h / 100 °C / Inert atmosphere

With dmap; oxo[hexa(trifluoroacetato)]tetrazinc; zinc trifluoromethanesulfonate; sodium hydride; Diethyl carbonate; In mineral oil;
DOI:10.1002/ejoc.201700748