Glycine, N-[N-(4-methoxybenzoyl)glycyl]-

Base Information

• Chemical Name: Glycine, N-[N-(4-methoxybenzoyl)glycyl]-
• CAS No.: 57463-79-3
• Molecular Formula: C12H14N2O5
• Molecular Weight: 266.254
• DSSTox Substance ID: DTXSID20364954
• Wikidata: Q82149205
• Mol file: 57463-79-3.mol

Synonyms:Glycine, N-[N-(4-methoxybenzoyl)glycyl]-;57463-79-3;2-[[2-[(4-methoxybenzoyl)amino]acetyl]amino]acetic acid;({[(4-methoxybenzoyl)amino]acetyl}amino)acetic acid;AG-690/09299018;DTXSID20364954;N-(4-methoxybenzoyl)glycylglycine;STL553893;AKOS001680949;N-[(4-methoxyphenyl)carbonyl]glycylglycine

Chemical Property of Glycine, N-[N-(4-methoxybenzoyl)glycyl]-

Chemical Property:

• XLogP3: -0.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 266.09027155
• Heavy Atom Count: 19
• Complexity: 337

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(=O)NCC(=O)NCC(=O)O

Technology Process of Glycine, N-[N-(4-methoxybenzoyl)glycyl]-

There total 6 articles about Glycine, N-[N-(4-methoxybenzoyl)glycyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

glycylglycine (556-50-3) + p-nitrophenyl p-methoxybenzoate (7464-46-2) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + [2-(4-Methoxy-benzoylamino)-acetylamino]-acetic acid (57463-79-3)

Guidance literature:

In water; dimethyl sulfoxide; at 25 ℃; Rate constant;

DOI:10.1139/cjc-76-6-729

Reference yield:

glycylglycine (556-50-3) + 2-chloro-4-nitrophenyl 4-methoxybenzoate → 2-chloro-4-nitrophenol (619-08-9) + [2-(4-Methoxy-benzoylamino)-acetylamino]-acetic acid (57463-79-3)

Guidance literature:

In water; dimethyl sulfoxide; acetonitrile; at 25 ℃; Kinetics; Mechanism;

DOI:10.5012/bkcs.2014.35.2.436

Reference yield:

4-methoxybenzoic acid 2,5-dioxo-1-pyrrolidinyl ester (30364-57-9) + glycylglycine (556-50-3) → 1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + [2-(4-Methoxy-benzoylamino)-acetylamino]-acetic acid (57463-79-3)

Guidance literature:

With potassium hydroxide; phosphate buffer; μ = 1.0; tetramethlyammonium chloride; In 1,4-dioxane; water; at 25 ℃; Rate constant; Mechanism; var. pH;

DOI:10.1021/jo00250a031

upstream raw materials:

4-methoxybenzoic acid 2,5-dioxo-1-pyrrolidinyl ester

glycylglycine

p-nitrophenyl p-methoxybenzoate

2,4-dinitrophenyl 4-methoxybenzoate