4-(4-Methylphenyl)-2-phenylphthalazin-1-one

Base Information

Chemical Name:4-(4-Methylphenyl)-2-phenylphthalazin-1-one
CAS No.:57709-75-8
Molecular Formula:C21H16N2O
Molecular Weight:312.371
Hs Code.:
DSSTox Substance ID:DTXSID10392761
Nikkaji Number:J2.978.297K
Wikidata:Q82191154

Synonyms:57709-75-8;4-(4-methylphenyl)-2-phenylphthalazin-1-one;2-Phenyl-4-(p-tolyl)phthalazin-1(2H)-one;2-Phenyl-4-p-tolylphthalazin-1(2H)-one;ST072007;Oprea1_379169;DTXSID10392761;AKOS003241342;CS-0453879;N16869;2-phenyl-4-p-tolyl-1,2-dihydrophthalazine-1-one;4-(4-methylphenyl)-2-phenylphthalazin-1(2H)-one;2-Phenyl-4-(4-methylphenyl)-1,2-dihydrophthalazine-1-one;4-(4-methylphenyl)-2-phenyl-1,2-dihydrophthalazin-1-one

Suppliers and Price of 4-(4-Methylphenyl)-2-phenylphthalazin-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-(4-Methylphenyl)-2-phenylphthalazin-1-one

Chemical Property:

XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:312.126263138
Heavy Atom Count:24
Complexity:486

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NN(C(=O)C3=CC=CC=C32)C4=CC=CC=C4

Technology Process of 4-(4-Methylphenyl)-2-phenylphthalazin-1-one

There total 4 articles about 4-(4-Methylphenyl)-2-phenylphthalazin-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 85-55-2
2-(4-toluoyl)benzoic acid

: 100-63-0
phenylhydrazine

: 57709-75-8
1-oxo-2-phenyl-4-p-tolyl-1,2-dihydrophthalazine

Guidance literature:: In toluene; Reflux;
DOI:10.3184/174751914X14116480062198

Reference yield: 85.0%

: 85-44-9
phthalic anhydride

: 100-63-0
phenylhydrazine

: 108-88-3,15644-74-3,16713-13-6
toluene

: 57709-75-8
1-oxo-2-phenyl-4-p-tolyl-1,2-dihydrophthalazine

Guidance literature:: phthalic anhydride; toluene; With montmorillonite KSF-H; In ethanol; Reflux;

phenylhydrazine; In ethanol; for 8h; regioselective reaction; Reflux;
DOI:10.1016/j.cclet.2009.11.032

Reference yield:

: 85-44-9
phthalic anhydride

: 108-88-3,15644-74-3,16713-13-6
toluene

: 57709-75-8
1-oxo-2-phenyl-4-p-tolyl-1,2-dihydrophthalazine

Guidance literature:: Multi-step reaction with 2 steps

1: HY-Zeolite / 1,2-dichloro-ethane / Reflux

2: 1,2-dichloro-ethane / Reflux

With HY-Zeolite; In 1,2-dichloro-ethane; 1: Friedel Crafts acylation;
DOI:10.1002/jhet.649