Technology Process of Propanoic acid, 2,2-dimethyl-, 4-(bromomethyl)phenyl ester
There total 4 articles about Propanoic acid, 2,2-dimethyl-, 4-(bromomethyl)phenyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
methanesulfonyl chloride; triethylamine; lithium bromide;
In
tetrahydrofuran;
at 0 ℃;
for 2h;
DOI:10.1021/jo051568z
- Guidance literature:
-
Multi-step reaction with 2 steps
1: KOH / dioxane
2: NBS; TPP / CH2Cl2
With
potassium hydroxide; N-Bromosuccinimide; thiamine diphosphate;
In
1,4-dioxane; dichloromethane;
1: Schotten-Baumann pivaloylation;
DOI:10.1021/np049796w
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 80 percent / sodium hydride / tetrahydrofuran / 2.5 h / 0 - 20 °C
2: 81 percent / lithium bromide; methanesulfonyl chloride; triethylamine / tetrahydrofuran / 2 h / 0 °C
With
sodium hydride; methanesulfonyl chloride; triethylamine; lithium bromide;
In
tetrahydrofuran;
DOI:10.1021/jo061395t
