Ethyl 4-[(3,4,5-trimethoxybenzoyl)amino]butanoate

Base Information

Chemical Name:Ethyl 4-[(3,4,5-trimethoxybenzoyl)amino]butanoate
CAS No.:58345-09-8
Molecular Formula:C16H23NO6
Molecular Weight:325.362
Hs Code.:
DSSTox Substance ID:DTXSID20369045
Wikidata:Q82156019

Synonyms:Ethyl 4-[(3,4,5-trimethoxybenzoyl)amino]butanoate;58345-09-8;DTXSID20369045;AKOS005219707

Suppliers and Price of Ethyl 4-[(3,4,5-trimethoxybenzoyl)amino]butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethyl 4-[(3,4,5-trimethoxybenzoyl)amino]butanoate

Chemical Property:

Melting Point:73-76 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling Point:423.8±45.0 °C(Predicted)
PSA：86.58000
Density:1.130±0.06 g/cm3(Predicted)
LogP:2.36030
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:10
Exact Mass:325.15253745
Heavy Atom Count:23
Complexity:362

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CCCNC(=O)C1=CC(=C(C(=C1)OC)OC)OC

Technology Process of Ethyl 4-[(3,4,5-trimethoxybenzoyl)amino]butanoate

There total 3 articles about Ethyl 4-[(3,4,5-trimethoxybenzoyl)amino]butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 6937-16-2
ethyl γ-aminobutyrate hydrochloride

: 4521-61-3
3,4,5-Trimethoxybenzoyl chloride

: 58345-09-8
4-(3,4,5-trimethoxy-benzoylamino)-butyric acid ethyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1021/jm060536g

Reference yield:

: 118-41-2
Eudesmic acid

: 58345-09-8
4-(3,4,5-trimethoxy-benzoylamino)-butyric acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride / N,N-dimethylformamide / CH₂Cl₂

2: 2.47 g / N-ethyl-N,N-diisopropylamine / CH₂Cl₂

With oxalyl dichloride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1021/jm060742o