2-(3,4,5-trimethoxyphenyl)-1H-indole

Base Information

Chemical Name:2-(3,4,5-trimethoxyphenyl)-1H-indole
CAS No.:58697-56-6
Molecular Formula:C17H17NO3
Molecular Weight:283.327
Hs Code.:
ChEMBL ID:CHEMBL571176
DSSTox Substance ID:DTXSID40567485
Nikkaji Number:J3.377.709D
Wikidata:Q82453382

Synonyms:2-(3,4,5-trimethoxyphenyl)-1H-indole;58697-56-6;CHEMBL571176;SCHEMBL11656533;DTXSID40567485

Suppliers and Price of 2-(3,4,5-trimethoxyphenyl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(3,4,5-trimethoxyphenyl)-1H-indole

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:283.12084340
Heavy Atom Count:21
Complexity:324

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1OC)OC)C2=CC3=CC=CC=C3N2

Technology Process of 2-(3,4,5-trimethoxyphenyl)-1H-indole

There total 8 articles about 2-(3,4,5-trimethoxyphenyl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1136-86-3
methyl (3,4,5-trimethoxyphenyl) ketone

: 100-63-0
phenylhydrazine

: 58697-56-6
2-(3,4,5-trimethoxyphenyl)-1H-indole

Guidance literature:: methyl (3,4,5-trimethoxyphenyl) ketone; phenylhydrazine; With acetic acid; In ethanol; at 80 ℃;

at 120 ℃;
DOI:10.1016/j.bmcl.2013.02.090

Reference yield: 65.0%

: 3958-60-9
2-nitrophenylmethyl bromide

: 188493-61-0
4-methyl-N′-(3,4,5-trimethoxybenzylidene)-benzenesulfonohydrazide

: 58697-56-6
2-(3,4,5-trimethoxyphenyl)-1H-indole

Guidance literature:: 2-nitrophenylmethyl bromide; 4-methyl-N′-(3,4,5-trimethoxybenzylidene)-benzenesulfonohydrazide; With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; trifuran-2-yl-phosphane; lithium tert-butoxide; In 1,4-dioxane; at 110 ℃; for 3h; Sealed tube; Inert atmosphere;

With triphenylphosphine; In 1,4-dioxane; at 160 ℃; for 24h;
DOI:10.1021/acs.joc.8b02623