2-(4-Methoxyphenyl)naphthalene

Base Information

• Chemical Name: 2-(4-Methoxyphenyl)naphthalene
• CAS No.: 59115-45-6
• Molecular Formula: C17H14O
• Molecular Weight: 234.298
• DSSTox Substance ID: DTXSID20456964
• Nikkaji Number: J1.784.351F
• Wikidata: Q82279614
• Mol file: 59115-45-6.mol

Synonyms:2-(4-methoxyphenyl)naphthalene;59115-45-6;Anisole,p-2-naphthyl-;SCHEMBL1896522;DTXSID20456964;HMJIYPQPQDOHRP-UHFFFAOYSA-N

Chemical Property of 2-(4-Methoxyphenyl)naphthalene

Chemical Property:

• Melting Point: 135-137℃ (ethanol )
• PSA: 9.23000
• LogP: 4.51540
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 234.104465066
• Heavy Atom Count: 18
• Complexity: 254

Purity/Quality:

99% ^*data from raw suppliers

2-(4-Methoxyphenyl)naphthalene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2=CC3=CC=CC=C3C=C2

Technology Process of 2-(4-Methoxyphenyl)naphthalene

There total 131 articles about 2-(4-Methoxyphenyl)naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

naphthalen-2-yl tosylate (7385-85-5) + 4-methoxyphenylboronic acid (5720-07-0) → 2-(4-methoxyphenyl)naphthalene (59115-45-6)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; potassium phosphate; tricyclohexylphosphine; In tetrahydrofuran; at 20 ℃; for 8h;

DOI:10.1021/ja038752r

Reference yield: 99.0%

2-bromonaphthalene (580-13-2) + 4-methoxyphenylboronic acid (5720-07-0) → 2-(4-methoxyphenyl)naphthalene (59115-45-6)

Guidance literature:

With potassium carbonate; [PS-PEG-adppp-Pd(η³-C3H5)]Cl; In water; at 50 ℃; for 12h;

DOI:10.1021/ol0264298

Reference yield: 98.0%

4-chloromethoxybenzene (623-12-1) + naphthalene-2-boronic acid (32316-92-0) → 2-(4-methoxyphenyl)naphthalene (59115-45-6)

Guidance literature:

With trans-chloro(9-phenanthrenyl)bis(triphenylphosphine)nickel(II); potassium carbonate; triphenylphosphine; In toluene; at 110 ℃; for 18h; Inert atmosphere;

DOI:10.1002/aoc.3000

upstream raw materials:

1-((4-methoxyphenyl)ethynyl)-2-vinylbenzene

naphthalene

2-naphthyl triflate

4-methoxyphenyltitanium triisopropoxide

Downstream raw materials:

2-(4′-hydroxyphenyl)naphthalene

6-naphthalen-2-yl-2,2-diphenyl-2H-chromene

dibromo-(4-methoxy-phenyl)-[2]naphthyl-λ⁴-tellane