Benzaldehyde, 3-acetyl-2,4,6-trihydroxy-5-methyl-

Base Information

Chemical Name:Benzaldehyde, 3-acetyl-2,4,6-trihydroxy-5-methyl-
CAS No.:59677-81-5
Molecular Formula:C10H10O5
Molecular Weight:210.186
Hs Code.:
ChEMBL ID:CHEMBL224756
DSSTox Substance ID:DTXSID70470256
Wikidata:Q82298280

Synonyms:59677-81-5;3-acetyl-2,4,6-trihydroxy-5-methylbenzaldehyde;Benzaldehyde, 3-acetyl-2,4,6-trihydroxy-5-methyl-;3-acetyl-2,4,6-trihydroxy-5-methyl-benzaldehyde;CHEMBL224756;DTXSID70470256

Suppliers and Price of Benzaldehyde, 3-acetyl-2,4,6-trihydroxy-5-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Benzaldehyde, 3-acetyl-2,4,6-trihydroxy-5-methyl-

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:210.05282342
Heavy Atom Count:15
Complexity:265

Purity/Quality:: HPLC≥98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=C(C(=C1O)C(=O)C)O)C=O)O

Technology Process of Benzaldehyde, 3-acetyl-2,4,6-trihydroxy-5-methyl-

There total 6 articles about Benzaldehyde, 3-acetyl-2,4,6-trihydroxy-5-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 62018-55-7
3'-formyl-2',4',6'-trihydroxyacetophenone

: 74-88-4
methyl iodide

: 59677-81-5
3-acetyl-2,4,6-trihydroxy-5-methylbenzaldehyde

Guidance literature:: 3'-formyl-2',4',6'-trihydroxyacetophenone; With potassium hydroxide; In methanol; Cooling with ice;

methyl iodide; In methanol; for 2h; Reflux;
DOI:10.1080/00397911.2014.930492

Reference yield:

: 480-66-0,67471-34-5
2,4,6-trihydroxyacetophenone

: 59677-81-5
3-acetyl-2,4,6-trihydroxy-5-methylbenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: POCl₃ / ethyl acetate / 0.5 h / 20 °C

2: potassium hydroxide / methanol / 2 h / Heating

With potassium hydroxide; trichlorophosphate; In methanol; ethyl acetate; 1: Vilsmeier-Haack formylation;
DOI:10.1016/j.bmc.2005.10.027

Reference yield:

: 108-73-6
3,5-dihydroxyphenol

: 59677-81-5
3-acetyl-2,4,6-trihydroxy-5-methylbenzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / AlCl₃ / CS₂ / 0.5 h / 50 °C

2: POCl₃ / ethyl acetate / 0.5 h / 20 °C

3: potassium hydroxide / methanol / 2 h / Heating

With potassium hydroxide; aluminium trichloride; trichlorophosphate; In methanol; carbon disulfide; ethyl acetate; 1: Friedel-Crafts reaction / 2: Vilsmeier-Haack formylation;
DOI:10.1016/j.bmc.2005.10.027