Ethyl 2-methyl-4-phenylnicotinate

Base Information

Chemical Name:Ethyl 2-methyl-4-phenylnicotinate
CAS No.:61209-74-3
Molecular Formula:C15H15NO2
Molecular Weight:241.29
Hs Code.:
DSSTox Substance ID:DTXSID40562632
Nikkaji Number:J3.558.681D
Wikidata:Q82446880

Synonyms:Ethyl 2-methyl-4-phenylnicotinate;61209-74-3;Ethyl 2-methyl-4-phenylpyridine-3-carboxylate;SCHEMBL9870996;Ethyl2-methyl-4-phenylnicotinate;DTXSID40562632;JHGQBYHIUKINFR-UHFFFAOYSA-N;ethyl 2-methyl-4-phenyl-3-pyridinecarboxylate;A849874

Suppliers and Price of Ethyl 2-methyl-4-phenylnicotinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Ethyl 2-methyl-4-phenylnicotinate

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:241.110278721
Heavy Atom Count:18
Complexity:274

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(C=CN=C1C)C2=CC=CC=C2

Technology Process of Ethyl 2-methyl-4-phenylnicotinate

There total 11 articles about Ethyl 2-methyl-4-phenylnicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1522-41-4
ethyl-2-fluoroacetoacetate

: 104-55-2
3-phenyl-propenal

: 61209-74-3
ethyl 2-methyl-4-phenylpyridine-3-carboxylate

Guidance literature:: With ammonium acetate; caesium carbonate; In acetonitrile; at 60 ℃; Reagent/catalyst; Temperature; regioselective reaction; Catalytic behavior;
DOI:10.1021/acs.orglett.6b02883

Reference yield: 55.0%

: ethyl 1-(4-methoxyphenylsulfonyl)-2-methyl-4-phenyl-1,6-dihydropyridine-3-carboxylate

: 61209-74-3
ethyl 2-methyl-4-phenylpyridine-3-carboxylate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; at 140 ℃;
DOI:10.1002/adsc.201600412

Reference yield: 34.0%

: 1721-26-2
ethyl 2-methyl nicotinate

: 98-80-6
phenylboronic acid

: 1702-14-3
ethyl 2-methyl-6-phenylnicotinate

: 61209-74-3
ethyl 2-methyl-4-phenylpyridine-3-carboxylate

Guidance literature:: ethyl 2-methyl nicotinate; phenylboronic acid; With Selectfluor; trifluoroacetic acid; In dichloromethane; water; at 20 ℃; for 0.0166667h;

With silver nitrate; In dichloromethane; water; at 50 ℃;
DOI:10.1021/acs.orglett.7b02706