phenyl(pyridin-2-yl)methyl benzoate

Base Information

• Chemical Name: phenyl(pyridin-2-yl)methyl benzoate
• CAS No.: 7463-83-4
• Molecular Formula: C19H15NO2
• Molecular Weight: 289.334
• Mol file: 7463-83-4.mol

Synonyms:

Chemical Property of phenyl(pyridin-2-yl)methyl benzoate

Chemical Property:

• Vapor Pressure: 1.36E-07mmHg at 25°C
• Boiling Point: 429.8°Cat760mmHg
• Flash Point: 213.7°C
• Density: 1.18g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of phenyl(pyridin-2-yl)methyl benzoate

There total 5 articles about phenyl(pyridin-2-yl)methyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-benzylpyridine-N-oxide (20531-86-6) + benzoyl chloride (98-88-4) → phenyl(pyridin-2-yl)methyl benzoate (7463-83-4)

Guidance literature:

With pyridine; In dichloromethane; at 0 - 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2020.152401

Reference yield:

benzoic acid (65-85-0,8013-63-6) + 3-phenyl-[1,2,3]triazolo[1,5-a]pyridine (832-81-5) → phenyl(pyridin-2-yl)methyl benzoate (7463-83-4)

Guidance literature:

at 190 - 210 ℃;

DOI:10.1021/ja01544a040

Reference yield:

2-Benzylpyridine (101-82-6) → phenyl(pyridin-2-yl)methyl benzoate (7463-83-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 5 h / 20 °C

2: pyridine / dichloromethane / 2 h / 0 - 20 °C

With pyridine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

DOI:10.1016/j.tetlet.2020.152401

upstream raw materials:

benzoic acid

3-phenyl-[1,2,3]triazolo[1,5-a]pyridine

2-benzylpyridine-N-oxide

benzoyl chloride