3,5-bis(4-bromophenyl)-1-phenyl-4,5-dihydro-1H-pyrazole

Base Information

Chemical Name:3,5-bis(4-bromophenyl)-1-phenyl-4,5-dihydro-1H-pyrazole
CAS No.:61595-99-1
Molecular Formula:C21H16Br2N2
Molecular Weight:456.179
Hs Code.:
DSSTox Substance ID:DTXSID60389146
Nikkaji Number:J2.004.495K
ChEMBL ID:CHEMBL2236663

Synonyms:61595-99-1;F0712-0068;3,5-bis(4-bromophenyl)-1-phenyl-4,5-dihydro-1H-pyrazole;SCHEMBL2687295;CHEMBL2236663;DTXSID60389146;3,5-Bis-(4-bromo-phenyl)-1-phenyl-4,5-dihydro-1H-pyrazole;AKOS001630884;1-Phenyl-3,5-bis(4-bromophenyl)-2-pyrazoline

Suppliers and Price of 3,5-bis(4-bromophenyl)-1-phenyl-4,5-dihydro-1H-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3,5-bis(4-bromophenyl)-1-phenyl-4,5-dihydro-1H-pyrazole

Chemical Property:

PSA：15.60000
LogP:6.06790
XLogP3:6.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:455.96597
Heavy Atom Count:25
Complexity:459

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(N(N=C1C2=CC=C(C=C2)Br)C3=CC=CC=C3)C4=CC=C(C=C4)Br

Technology Process of 3,5-bis(4-bromophenyl)-1-phenyl-4,5-dihydro-1H-pyrazole

There total 8 articles about 3,5-bis(4-bromophenyl)-1-phenyl-4,5-dihydro-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 5471-96-5
1,3-bis(4-bromophenyl)-2-propen-1-one

: 100-63-0
phenylhydrazine

: 61595-99-1
3-(4-bromophenyl)-5-(4-bromophenyl)-1-phenyl-2-pyrazoline

Guidance literature:: With acetic acid; for 6h; Reflux;
DOI:10.1007/s00044-011-9735-9

Reference yield:

: 5471-96-5,126443-21-8
(E)-1,3-bis(4-bromophenyl)prop-2-en-1-one

: 100-63-0
phenylhydrazine

: 61595-99-1
3-(4-bromophenyl)-5-(4-bromophenyl)-1-phenyl-2-pyrazoline

Guidance literature:: With acetic acid;

Reference yield:

: 99-90-1
para-bromoacetophenone

: 61595-99-1
3-(4-bromophenyl)-5-(4-bromophenyl)-1-phenyl-2-pyrazoline

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol / Heating

2: sulfuric acid / ethanol / 20 °C / Reflux

With sulfuric acid; sodium hydroxide; In ethanol;
DOI:10.1016/j.catcom.2013.09.002