1-(2-Furanyl)ethanone phenyl hydrazone

Base Information

• Chemical Name: 1-(2-Furanyl)ethanone phenyl hydrazone
• CAS No.: 61726-90-7
• Molecular Formula: C12H12N2O
• Molecular Weight: 200.24
• Hs Code.: 2934999090
• Mol file: 61726-90-7.mol

Synonyms:

Chemical Property of 1-(2-Furanyl)ethanone phenyl hydrazone

Chemical Property:

• PSA: 37.53000
• LogP: 3.18870

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2-Furanyl)ethanone phenyl hydrazone

There total 3 articles about 1-(2-Furanyl)ethanone phenyl hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1-(2-furyl)-1-ethanone (1192-62-7,80145-44-4) + phenylhydrazine hydrochloride (59-88-1) → 1-(1-(furan-2-yl)ethylidene)-2-phenylhydrazine (61726-90-7)

Guidance literature:

With sodium acetate; In ethanol; at 80 ℃; for 0.0833333h; Microwave irradiation; air-cooling;

DOI:10.1021/co100015b

Reference yield: 80.0%

1-(2-furyl)-1-ethanone (1192-62-7,80145-44-4) + phenyl hydrazine hydrochloride → 1-(1-(furan-2-yl)ethylidene)-2-phenylhydrazine (61726-90-7)

Guidance literature:

With sodium acetate; In ethanol; at 25 - 100 ℃; for 0.116667h; Microwave irradiation;

Reference yield:

1-(2-furyl)-1-ethanone (1192-62-7,80145-44-4) + phenylhydrazine (100-63-0) → 1-(1-(furan-2-yl)ethylidene)-2-phenylhydrazine (61726-90-7)

Guidance literature:

DOI:10.1039/jr9590000657

upstream raw materials:

1-(2-furyl)-1-ethanone

phenylhydrazine

phenylhydrazine hydrochloride

Downstream raw materials:

aniline

4-chloro-aniline

4-methoxy-aniline

Refernces

• 1、 Vetokhina, Volha,Kijak, Micha?,Lipinska, Teodozja M.,Thummel, Randolph P.,Sepiol, Jerzy,Waluk, Jacek,Herbich, Jerzy. "Spectroscopy and photophysics of bifunctional proton donor-acceptor indole derivatives". . p. 4898 - 4906. Retrieved 2013/07/19.
• 2、 La Regina, Giuseppe,Bai, Ruoli,Rensen, Willeke,Coluccia, Antonio,Piscitelli, Francesco,Gatti, Valerio,Bolognesi, Alessio,Lavecchia, Antonio,Granata, Ilaria,Porta, Amalia,Maresca, Bruno,Soriani, Alessandra,Iannitto, Maria Luisa,Mariani, Marisa,Santoni, Angela,Brancale, Andrea,Ferlini, Cristiano,Dondio, Giulio,Varasi, Mario,Mercurio, Ciro,Hamel, Ernest,Lavia, Patrizia,Novellino, Ettore,Silvestri, Romano. "Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability". experimental part. p. 8394 - 8406. Retrieved 2012/02/14.