9-(2-bromoethyl)adenine

Base Information

• Chemical Name: 9-(2-bromoethyl)adenine
• CAS No.: 68217-74-3
• Molecular Formula: C7H8BrN5
• Molecular Weight: 242.078
• Hs Code.: 2933990090
• Mol file: 68217-74-3.mol

Synonyms:9H-Purin-6-amine,9-(2-bromoethyl);6-amino-9-(2-bromoethyl)-9H-purine;9-(2-bromoethyl)-9H-6-purinamine;9-(2-bromoethyl)-9h-purin-6-amine;9-(2-bromoethyl)-adenine;

Chemical Property of 9-(2-bromoethyl)adenine

Chemical Property:

• Vapor Pressure: 5.65E-08mmHg at 25°C
• Boiling Point: 441°Cat760mmHg
• Flash Point: 220.5°C
• PSA: 69.62000
• Density: 1.97g/cm³
• LogP: 1.38460
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

97% ^*data from raw suppliers

9-(2-Bromoethyl)-9H-purin-6-amine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9-(2-bromoethyl)adenine

There total 3 articles about 9-(2-bromoethyl)adenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ethylene dibromide (106-93-4) + adenine (66224-66-6,66224-67-7,66224-68-8,66224-69-9,134434-48-3,134434-49-4,134454-76-5,134461-75-9) → 9‐(2‐bromoethyl)‐9H‐purin‐6‐amine (68217-74-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 10h;

DOI:10.1016/j.bmcl.2008.09.051

Reference yield: 53.0%

7H-purin-6-ylamine (73-24-5,71660-29-2,71660-30-5) + ethylene dibromide (106-93-4) → 9‐(2‐bromoethyl)‐9H‐purin‐6‐amine (68217-74-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1002/ejoc.202100786

Reference yield: 48.0%

9-(2-hydroxyethyl)adenine (707-99-3) → 9‐(2‐bromoethyl)‐9H‐purin‐6‐amine (68217-74-3)

Guidance literature:

With sulfurous dibromide; for 0.333333h; Ambient temperature;

upstream raw materials:

ethylene dibromide

adenine

9-(2-hydroxyethyl)adenine

7H-purin-6-ylamine

Downstream raw materials:

3-(2-(6-amino-9H-purin-9-yl)ethoxy)-2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one

N-[2-(6-amino-purin-9-yl)-ethyl]-phthalimide