Dimethyl pyridin-2-ylphosphonate

Base Information

• Chemical Name: Dimethyl pyridin-2-ylphosphonate
• CAS No.: 61864-97-9
• Molecular Formula: C7H10NO3P
• Molecular Weight: 187.135
• DSSTox Substance ID: DTXSID20577204
• Wikidata: Q82467149
• Mol file: 61864-97-9.mol

Synonyms:61864-97-9;Dimethyl pyridin-2-ylphosphonate;DTXSID20577204

Chemical Property of Dimethyl pyridin-2-ylphosphonate

Chemical Property:

• XLogP3: 0.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 187.03983018
• Heavy Atom Count: 12
• Complexity: 178

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COP(=O)(C1=CC=CC=N1)OC

Technology Process of Dimethyl pyridin-2-ylphosphonate

There total 2 articles about Dimethyl pyridin-2-ylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

tris(2-pyridyl)phosphine (26437-48-9) → [2,2]bipyridinyl (366-18-7) + 5-bromo-2,2'-bipyridyl (15862-19-8) + dimethyl pyridin-2-yl-2-phosphonate (61864-97-9)

Guidance literature:

With bromine; In methanol;

DOI:10.1080/10426509608545226

Reference yield: 14.0%

methanol (67-56-1) + tris(2-pyridyl)phosphine (26437-48-9) → [2,2]bipyridinyl (366-18-7) + 5-bromo-2,2'-bipyridyl (15862-19-8) + dimethyl pyridin-2-yl-2-phosphonate (61864-97-9)

Guidance literature:

With bromine; Product distribution; electrophilic substitution on tris(2-pyridyl)phosphine;

DOI:10.1080/10426509608545226

upstream raw materials:

methanol

tris(2-pyridyl)phosphine