Propanamide, N,N-diethyl-2-methyl-

Base Information

• Chemical Name: Propanamide, N,N-diethyl-2-methyl-
• CAS No.: 33931-44-1
• Molecular Formula: C8H17NO
• Molecular Weight: 143.229
• Hs Code.: 2924199090
• Mol file: 33931-44-1.mol

Synonyms:Isobuttersaeure-diaethylamid;N,N-diethyl-isobutyramide;N,N-diethyl 2-methylpropionamide;Propanamide,N,N-diethyl-2-methyl;Isobutyryldiaethylamin;N,N-Diaethyl-isobutyramid;N,N-diethylisobutyric amide;

Chemical Property of Propanamide, N,N-diethyl-2-methyl-

Chemical Property:

• Vapor Pressure: 0.331mmHg at 25°C
• Boiling Point: 200°Cat760mmHg
• Flash Point: 73.6°C
• PSA: 20.31000
• Density: 0.866g/cm³
• LogP: 1.51080

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propanamide, N,N-diethyl-2-methyl-

There total 6 articles about Propanamide, N,N-diethyl-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

N,N-diethylmethacrylamide (5441-99-6) → N,N-diethylisobutyramide (33931-44-1) + N,N-diethyl 2-methyl-2-formylpropionamide + N,N-diethyl 2-methyl-3-formylpropionamide (129549-45-7) + 3-methyltetrahydro-2-furanone (1679-47-6)

Guidance literature:

With dodecacarbonyltetrarhodium⁽⁰⁾; (-)-Diop; hydrogen; In toluene; at 130 ℃; for 32h; under 225018 Torr; Further byproducts given;

DOI:10.1016/0022-328X(90)80010-W

Reference yield: 33.0%

N,N-diethylmethacrylamide (5441-99-6) + carbon monoxide (201230-82-2) → N,N-diethylisobutyramide (33931-44-1) + N,N-diethyl 2-methyl-2-formylpropionamide + N,N-diethyl 2-methyl-3-formylpropionamide (129549-45-7) + 3-methyltetrahydro-2-furanone (1679-47-6)

Guidance literature:

With dodecacarbonyltetrarhodium⁽⁰⁾; (-)-Diop; hydrogen; In toluene; at 130 ℃; for 32h; under 225018 Torr; Further byproducts given;

DOI:10.1016/0022-328X(90)80010-W

Reference yield: 24.0%

N,N-diethylmethacrylamide (5441-99-6) + carbon monoxide (201230-82-2) → N,N-diethylisobutyramide (33931-44-1) + N,N-diethyl 2-methyl-4-(diethylamino)butyramide (100798-82-1) + N,N-diethyl 2-methyl-4-hydroxybutyramide (129549-46-8) + 3-methyltetrahydro-2-furanone (1679-47-6)

Guidance literature:

With dodecacarbonyltetrarhodium⁽⁰⁾; hydrogen; In toluene; at 130 ℃; for 26h; under 225018 Torr; Title compound not separated from byproducts;

DOI:10.1016/0022-328X(90)80010-W

upstream raw materials:

triethylamine

isobutyryl chloride

diethyl ether

lithium diethylamide

Downstream raw materials:

N,N-Diethyl-2-methyl-2-benzyl-propionsaeureamid

1-(2,4-dimethoxyphenyl)-2-methylpropan-1-one

2-methyl-1-(2-furyl)-1-propanone