(1-phenylethyl)malononitrile

Base Information

• Chemical Name: (1-phenylethyl)malononitrile
• CAS No.: 61925-48-2
• Molecular Formula: C₁₁H₁₀N₂
• Molecular Weight: 170.214
• Mol file: 61925-48-2.mol

Synonyms:

Chemical Property of (1-phenylethyl)malononitrile

Chemical Property:

• PSA: 47.58000
• LogP: 2.45346

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1-phenylethyl)malononitrile

There total 13 articles about (1-phenylethyl)malononitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-(1-phenylethylidene)propanedinitrile (5447-87-0) → 2-(1-phenylethyl)propanedinitrile (29621-69-0,61925-48-2,51084-12-9)

Guidance literature:

With 2-phenylthiazoline; aluminium trichloride; In butan-1-ol; for 24h; Heating;

Reference yield: 88.0%

2-(1-phenylethylidene)propanedinitrile (5447-87-0) → 2-(1-phenylethyl)propanedinitrile (29621-69-0,61925-48-2,51084-12-9) + 2-phenyl-1H-benzoimidazole (716-79-0)

Guidance literature:

With benzaldehyde; 1,2-diamino-benzene; In ethanol; for 9h; Ambient temperature;

Reference yield: 70.0%

acetophenone (98-86-2) + malononitrile (109-77-3) → 2-(1-phenylethyl)propanedinitrile (29621-69-0,61925-48-2,51084-12-9)

Guidance literature:

With formic acid; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; triethylamine; In dichloromethane; at 40 ℃; for 8h; Inert atmosphere;

DOI:10.1080/00397911.2010.481741

upstream raw materials:

2-(1-phenylethylidene)propanedinitrile

1,1,1,2,2,2-hexamethyldisilane

Benzylidenemalononitrile

acetophenone

Downstream raw materials:

3-phenyl-butyric acid methyl ester

2-(1-phenylethylidene)propanedinitrile

C₂₈H₂₅N₃O₅

3-phenylbutyric acid

Refernces

• 1、 Morofuji, Tatsuya,Matsui, Yu,Ohno, Misa,Ikarashi, Gun,Kano, Naokazu. "Photocatalytic Giese-Type Reaction with Alkylsilicates Bearing C,O-Bidentate Ligands". supporting information. p. 6713 - 6718. Retrieved 2021/02/26.
• 2、 Deng, Yuchao,Fagnoni, Maurizio,Guthrie, Duncan,Laudadio, Gabriele,No?l, Timothy,Nun?, Manuel,Ravelli, Davide,Sun, Yuhan,Wal, Klaas Van Der. "C(sp3)-H functionalizations of light hydrocarbons using decatungstate photocatalysis in flow". . p. 92 - 96. Retrieved 2020/09/03.