Hexamethyldisilane

Base Information

• Chemical Name: Hexamethyldisilane
• CAS No.: 1450-14-2
• Molecular Formula: C6H18Si2
• Molecular Weight: 146.38
• Hs Code.: 29310095
• European Community (EC) Number: 215-911-0
• NSC Number: 294211
• UNII: A7HH2E9DUB
• DSSTox Substance ID: DTXSID2061698
• Nikkaji Number: J21.128A
• Wikipedia: Hexamethyldisilane
• Wikidata: Q1032896
• Mol file: 1450-14-2.mol

Synonyms:Disilane, hexamethyl-(6CI,7CI,8CI,9CI);NSC 294211;Permethyldisilane;Hexamethyldisilane (HMD);

Chemical Property of Hexamethyldisilane

Chemical Property:

• Appearance/Colour: Colorless clear liquid
• Vapor Pressure: 24.5mmHg at 25°C
• Melting Point: 9-12 °C(lit.)
• Refractive Index: n20/D 1.422(lit.)
• Boiling Point: 113.5 °C at 760 mmHg
• Flash Point: 5.8 °C
• PSA: 0.00000
• Density: 0.735 g/cm³
• LogP: 2.74120
• Storage Temp.: Flammables area
• Solubility.: sol common organic solvents; insol H2O.
• Water Solubility.: Insoluble in water. Soluble in alcohol, ether and acetone.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 146.09470364
• Heavy Atom Count: 8
• Complexity: 61.5

Purity/Quality:

≥99.0% ^*data from raw suppliers

Hexamethyldisilane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,Xi
• Hazard Codes: F,Xi
• Statements: 11-36/37-43-36/37/38
• Safety Statements: 16-23-45-9-33-26-7/9

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Metalloid Compounds (Silicon)
• Canonical SMILES: C[Si](C)(C)[Si](C)(C)C
• Uses: Hexamethyldisilane acts as a silylating reagent for allylic acetates, aryl halides and diketones. It is a source material for vapor deposition during silicon carbide growth. It is also used in electronic and semiconducter industries.

Technology Process of Hexamethyldisilane

There total 110 articles about Hexamethyldisilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

benzophenone (119-61-9) + (trimethylsilyl)potassium (56859-17-7) → 1,1,1,2,2,2-hexamethyldisilane (1450-14-2) + tetraphenylethane-1,2-diol (464-72-2)

Guidance literature:

In 1,2-dimethoxyethane; for 12h; Ambient temperature;

Reference yield: 68.0%

bis(trimethylsilyl)diphenylgermane (111655-78-8) + 2,3-dimethyl-buta-1,3-diene (513-81-5) → 1,1,1,2,2,2-hexamethyldisilane (1450-14-2) + trimethylphenylsilane (768-32-1) + 1,1-diphenyl-3,4-dimethyl-1-germacyclopent-3-ene (5764-69-2)

Guidance literature:

In pentane; Irradiation (UV/VIS); (N2), 1 h irradiated; gas chromatography; elem. anal., NMR, mass. spectra;

DOI:10.1021/om00054a046

Reference yield: 60.0%

methyl(phenyl)bis(trimethylsilyl)germane (134847-65-7) + 2,3-dimethyl-buta-1,3-diene (513-81-5) → 1,1,1,2,2,2-hexamethyldisilane (1450-14-2) + 1,3,4-trimethyl-1-(trimethylsilyl)-1-germacyclopent-3-ene (134847-66-8) + (2,3-dimethyl-3-butenyl)methyl(trimethylsilyl){o-(trimethylsilyl)phenyl}germane (134847-67-9) + trimethylphenylsilane (768-32-1) + 1,3,4-trimethyl-1-phenyl-1-germacyclopent-3-ene (51533-82-5)

Guidance literature:

In pentane; Irradiation (UV/VIS); (N2), 1.5 h irradiated; column chromatography; elem. anal., NMR, mass. spectra;

DOI:10.1021/om00054a046

upstream raw materials:

chloro-trimethyl-silane

trimethylsilylethane

trimethylsilyl iodide

trimethylphenylsilane

Downstream raw materials:

(2,6-Dibromo-4-methanesulfonyl-phenoxy)-trimethyl-silane

1,1,2-trichloro-1,2,2-trimethyldisilane

1,1,2,2-tetrachloro-1,2-dimethyldisilane

1-(trimethylsilyl)-1-hexyne

Refernces

• 1、 Siedschlag, Randall B.,Bernales, Varinia,Vogiatzis, Konstantinos D.,Planas, Nora,Clouston, Laura J.,Bill, Eckhard,Gagliardi, Laura,Lu, Connie C.. "Catalytic Silylation of Dinitrogen with a Dicobalt Complex". . p. 4638 - 4641. Retrieved 2015.
• 2、 Gordetsov, A. S.,Zimina, S. V.,Skobeleva, S. E.,Makarenko, N. P.,Cherkasov, V. K.,et al.. "". . . Retrieved 1988.
• 3、 Marr,Webster. "". . p. 202. Retrieved 1968.
• 4、 Eaborn et al.. "". . p. 920. Retrieved 1967.
• 5、 Lickiss, Paul D.,Lucas, Ronan. "Ultrasound in organometallic chemistry. The effects of temperature, metal purity and power source on the ultrasound-promoted reaction between trimethylchlorosilane and lithium". . p. 25 - 28. Retrieved 1993.
• 6、 Castro-Rodriguez, Ingrid,Nakai, Hidetaka,Meyer, Karsten. "Multiple-bond metathesis mediated by sterically pressured uranium complexes". . p. 2389 - 2392. Retrieved 2006.
• 7、 Tanaka, Hiromasa,Sasada, Akira,Kouno, Tomohisa,Yuki, Masahiro,Miyake, Yoshihiro,Nakanishi, Haruyuki,Nishibayashi, Yoshiaki,Yoshizawa, Kazunari. "Molybdenum-catalyzed transformation of molecular dinitrogen into silylamine: Experimental and DFT study on the remarkable role of ferrocenyldiphosphine ligands". . p. 3498 - 3506. Retrieved 2011.
• 8、 Sundermeyer. "". . p. 50. Retrieved 1961.
• 9、 Sakurai,Okada. "". . p. C13. Retrieved 1972.
• 10、 Sharma, Sneh,Kapoor, Ramesh N.,Cervantes-Lee, Francisco,Pannell, Keith H.. "". . p. 1177 - 1188. Retrieved 1991.