1H-Pyrazole-3-carboxylic acid, 1-(4-methylphenyl)-5-phenyl-, ethyl ester

Base Information

Chemical Name:1H-Pyrazole-3-carboxylic acid, 1-(4-methylphenyl)-5-phenyl-, ethyl ester
CAS No.:62160-89-8
Molecular Formula:C19H18N2O2
Molecular Weight:306.35800
Hs Code.:
DSSTox Substance ID:DTXSID10466299
Wikidata:Q82292834

Synonyms:62160-89-8;1H-Pyrazole-3-carboxylic acid, 1-(4-methylphenyl)-5-phenyl-, ethyl ester;DTXSID10466299;ETHYL 1-(4-METHYLPHENYL)-5-PHENYLPYRAZOLE-3-CARBOXYLATE

Suppliers and Price of 1H-Pyrazole-3-carboxylic acid, 1-(4-methylphenyl)-5-phenyl-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1H-Pyrazole-3-carboxylic acid, 1-(4-methylphenyl)-5-phenyl-, ethyl ester

Chemical Property:

PSA：44.12000
LogP:4.02440
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:306.136827821
Heavy Atom Count:23
Complexity:387

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=NN(C(=C1)C2=CC=CC=C2)C3=CC=C(C=C3)C

Technology Process of 1H-Pyrazole-3-carboxylic acid, 1-(4-methylphenyl)-5-phenyl-, ethyl ester

There total 3 articles about 1H-Pyrazole-3-carboxylic acid, 1-(4-methylphenyl)-5-phenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 88330-79-4,244277-46-1
ethyl-(Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoate

: 539-44-6
N-4-methylphenylhydrazine

: 62160-89-8
3-ethoxycarbonyl-1-(4-methylphenyl)-5-phenyl-1H-pyrazole

Guidance literature:: In ethanol; for 3h; Heating;
DOI:10.1021/jm0407761

Reference yield:

: 98-86-2
acetophenone

: 62160-89-8
3-ethoxycarbonyl-1-(4-methylphenyl)-5-phenyl-1H-pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / EtONa / ethanol / 2 h / Heating

2: 80 percent / ethanol / 3 h / Heating

With sodium ethanolate; In ethanol;
DOI:10.1021/jm0407761