7-Methoxy-3-phenylisoquinolin-1(2H)-one

Base Information

Chemical Name:7-Methoxy-3-phenylisoquinolin-1(2H)-one
CAS No.:62265-91-2
Molecular Formula:C16H13NO2
Molecular Weight:251.285
Hs Code.:
DSSTox Substance ID:DTXSID40453112
Nikkaji Number:J3.206.487F
Wikidata:Q82274127

Synonyms:62265-91-2;7-Methoxy-3-phenylisoquinolin-1(2H)-one;CTK2C3550;DTXSID40453112;3-Phenyl-7-methoxy-1,2-dihydroisoquinoline-1-one

Suppliers and Price of 7-Methoxy-3-phenylisoquinolin-1(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 7-Methoxy-3-phenylisoquinolin-1(2H)-one

Chemical Property:

PSA：42.35000
LogP:3.61600
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:251.094628657
Heavy Atom Count:19
Complexity:371

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C=C(NC2=O)C3=CC=CC=C3

Technology Process of 7-Methoxy-3-phenylisoquinolin-1(2H)-one

There total 10 articles about 7-Methoxy-3-phenylisoquinolin-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 99848-43-8
2-bromo-5-methoxybenzamide

: 98-86-2
acetophenone

: 62265-91-2
7-methoxy-3-phenylisoquinolin-1(2H)-one

Guidance literature:: With caesium carbonate; copper(I) bromide; In dimethyl sulfoxide; at 80 ℃; for 24h; Inert atmosphere; Sealed tube; Schlenk technique;
DOI:10.1002/chem.201301621

Reference yield: 72.0%

: 14963-94-1
7-methoxy-3-phenyl-1H-isochromen-1-one

: 62265-91-2
7-methoxy-3-phenylisoquinolin-1(2H)-one

Guidance literature:: With ammonium acetate; In N,N-dimethyl acetamide; at 120 ℃;
DOI:10.1016/j.tet.2020.131437

Reference yield: 15.0%

: methyl 5-methoxy-2-(2-phenylethynyl)benzoate

: 62265-91-2
7-methoxy-3-phenylisoquinolin-1(2H)-one

: (Z)-3-benzylidene-6-methoxyisoindolin-1-one

Guidance literature:: methyl 5-methoxy-2-(2-phenylethynyl)benzoate; With trifluorormethanesulfonic acid; In acetonitrile; at 85 ℃; Inert atmosphere; Sealed tube;

With piperidine; In acetonitrile; at 20 ℃; for 0.5h;

With ammonium acetate; In N,N-dimethyl acetamide; at 120 ℃;
DOI:10.1016/j.tet.2020.131437