4-(Dimethylamino)phenyl ethyl sulfide

Base Information

• Chemical Name: 4-(Dimethylamino)phenyl ethyl sulfide
• CAS No.: 62291-59-2
• Molecular Formula: C10H15NS
• Molecular Weight: 181.302
• DSSTox Substance ID: DTXSID40488621
• Nikkaji Number: J1.502.795I
• Wikidata: Q82331402
• Mol file: 62291-59-2.mol

Synonyms:4-(Dimethylamino)phenyl ethyl sulfide;62291-59-2;4-(Ethylthio)-N,N-dimethylaniline;4-ethylsulfanyl-N,N-dimethylaniline;DTXSID40488621;AKOS006318211;4-(Ethylsulfanyl)-N,N-dimethylaniline;(4-Ethylsulfanyl-phenyl)-dimethyl-amine

Chemical Property of 4-(Dimethylamino)phenyl ethyl sulfide

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 181.09252066
• Heavy Atom Count: 12
• Complexity: 117

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCSC1=CC=C(C=C1)N(C)C

Technology Process of 4-(Dimethylamino)phenyl ethyl sulfide

There total 5 articles about 4-(Dimethylamino)phenyl ethyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethyl bromide (74-96-4) + N,N-dimethyl-4-aminothiophenol (4946-22-9,656242-02-3) → 4-(ethylthio)-N,N-dimethylaniline (62291-59-2)

Guidance literature:

With sodium hydroxide; In methanol; at 20 ℃; for 4h;

DOI:10.1021/jacs.7b03887

Reference yield: 63.0%

ethanol (64-17-5) + N,N-dimethyl-aniline (121-69-7,77733-26-7) → 4-(ethylthio)-N,N-dimethylaniline (62291-59-2)

Guidance literature:

With potassium thioacyanate; In water; at 20 ℃; for 20h; Electrolysis; Inert atmosphere; Green chemistry;

DOI:10.1039/d0gc00591f

Reference yield: 62.0%

p-dimethylaminoselenoanisole (2388-51-4) + methyl iodide (74-88-4) → 4-(ethylthio)-N,N-dimethylaniline (62291-59-2) + p-Dimethylaminophenyl-isopropyl-sulfid (62291-60-5) + (4-ethylsulfanyl-2-methyl-phenyl)-dimethyl-amine + 4-(ethylthio)-N,N,3-trimethylaniline

Guidance literature:

With LICKOR; In hexane; at -40 - 20 ℃; for 1h;

DOI:10.1016/S0022-328X(00)00806-8

upstream raw materials:

ethanol

4-(dimethylamino)benzenethiocyanate

p-dimethylaminoselenoanisole

methyl iodide