1,4-Bis(chloromethyl)-2,5-diethoxybenzene

Base Information

• Chemical Name: 1,4-Bis(chloromethyl)-2,5-diethoxybenzene
• CAS No.: 56150-29-9
• Molecular Formula: C12H16Cl2O2
• Molecular Weight: 263.164
• European Community (EC) Number: 661-313-1
• NSC Number: 25495
• DSSTox Substance ID: DTXSID40282343
• Wikidata: Q82016597
• Mol file: 56150-29-9.mol

Synonyms:56150-29-9;1,4-bis(chloromethyl)-2,5-diethoxybenzene;NSC25495;SCHEMBL7957708;DTXSID40282343;NSC-25495;AKOS024339493;1,4-diethoxy-2,5-bis (chloromethyl)benzene;1,4-BIS(CHLOROMETHYL)-2,5-DIETHOXY-BENZENE

Chemical Property of 1,4-Bis(chloromethyl)-2,5-diethoxybenzene

Chemical Property:

• Vapor Pressure: 5.56E-05mmHg at 25°C
• Boiling Point: 357.6°Cat760mmHg
• Flash Point: 129°C
• Density: 1.165g/cm³
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 262.0527351
• Heavy Atom Count: 16
• Complexity: 170

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=CC(=C(C=C1CCl)OCC)CCl

Technology Process of 1,4-Bis(chloromethyl)-2,5-diethoxybenzene

There total 2 articles about 1,4-Bis(chloromethyl)-2,5-diethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1,4-diethoxybenzene (122-95-2) → 1,4-diethoxy-2,5-bis(chloromethyl)benzene (56150-29-9)

Guidance literature:

With hydrogenchloride; phosphoric acid; mercury;

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1,4-diethoxybenzene (122-95-2) → 1,4-diethoxy-2,5-bis(chloromethyl)benzene (56150-29-9) + 1,4-diethoxy-2-chloromethyl-benzene (103861-41-2)

Guidance literature:

With hydrogenchloride; phosphoric acid; mercury; unter Einleiten von HCl;

Reference yield: 87.0%

methanol (67-56-1) + 1,4-diethoxy-2,5-bis(chloromethyl)benzene (56150-29-9) → 1,4-diethoxy-2,5-bis(methoxymethyl)benzene (1207685-09-3)

Guidance literature:

With sodium methylate; Reflux;

DOI:10.1007/s10847-012-0242-5

upstream raw materials:

formaldehyd

1,4-diethoxybenzene

Downstream raw materials:

(2,5-diethoxy-p-phenylene)-di-acetonitrile

(2,5-diethoxy-p-phenylene)-di-acetic acid

2,5-Diethoxy-1,4-phenylendiacetylchlorid

2,5-bis(n-butoxymethyl)-1,4-diethoxybenzene