Benzoic acid, 2,2'-[(1,3-dioxo-1,3-propanediyl)diimino]bis-, dimethyl ester

Base Information

• Chemical Name: Benzoic acid, 2,2'-[(1,3-dioxo-1,3-propanediyl)diimino]bis-, dimethyl ester
• CAS No.: 62640-76-0
• Molecular Formula: C19H18N2O6
• Molecular Weight: 370.362
• Mol file: 62640-76-0.mol

Synonyms:N,N'-malonyl-di-anthranilic acid dimethyl ester;N,N'-Malonyl-bis-(2-amino-benzoesaeure-methylester);2,2'-(Malonyldiimino)bisbenzoesaeuredimethylester;N,N'-Malonyl-di-anthranilsaeure-dimethylester;

Chemical Property of Benzoic acid, 2,2'-[(1,3-dioxo-1,3-propanediyl)diimino]bis-, dimethyl ester

Chemical Property:

• PSA: 110.80000
• LogP: 2.37310

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 2,2'-[(1,3-dioxo-1,3-propanediyl)diimino]bis-, dimethyl ester

There total 4 articles about Benzoic acid, 2,2'-[(1,3-dioxo-1,3-propanediyl)diimino]bis-, dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

ethyl 2-(o-methoxycarbonylphenyl)carbamoylacetate (159657-34-8) → N,N'-di-2-carbomethoxyanilide of malonic acid (62640-76-0) + diethyl malonate (105-53-3)

Guidance literature:

In N,N-dimethyl-formamide; for 5h; Heating;

DOI:10.1016/S0040-4020(01)81765-8

Reference yield:

2-carbomethoxyaniline (134-20-3) → N,N'-di-2-carbomethoxyanilide of malonic acid (62640-76-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / Et₃N / acetone / Ambient temperature

2: 91 percent / dimethylformamide / 5 h / Heating

With triethylamine; In N,N-dimethyl-formamide; acetone;

DOI:10.1016/S0040-4020(01)81765-8

Reference yield:

2-carbomethoxyaniline (134-20-3) + malonic acid dimethyl ester (108-59-8) → N,N'-di-2-carbomethoxyanilide of malonic acid (62640-76-0)

Guidance literature:

upstream raw materials:

2-carbomethoxyaniline

malonic acid dimethyl ester

ethyl 2-(o-methoxycarbonylphenyl)carbamoylacetate