Methyl 4-phenyl-1H-pyrazole-3-carboxylate

Base Information

Chemical Name:Methyl 4-phenyl-1H-pyrazole-3-carboxylate
CAS No.:5932-28-5
Molecular Formula:C19H21N3O4
Molecular Weight:202.213
Hs Code.:
Mol file:5932-28-5.mol

Synonyms:Methyl 4-phenyl-1H-pyrazole-3-carboxylate;methyl 4-phenyl-1H-pyrazole-5-carboxylate;856061-35-3;SCHEMBL949763;4-phenyl-1H-pyrazole-3-carboxylic acid methyl ester;1H-Pyrazole-3-carboxylic acid, 4-phenyl-, methyl ester;AKOS016001652;AKOS022178690;A869223;4-phenyl-2H-pyrazole-3-carboxylic acid methyl ester

Suppliers and Price of Methyl 4-phenyl-1H-pyrazole-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl4-phenyl-1H-pyrazole-3-carboxylate 95+%
1g
$ 614.00

American Custom Chemicals Corporation
METHYL-4-PHENYL-1H-PYRAZOLE-3-CARBOXYLATE 95.00%
5MG
$ 498.17

Total 9 raw suppliers

Chemical Property of Methyl 4-phenyl-1H-pyrazole-3-carboxylate

Chemical Property:

Vapor Pressure:1.08E-11mmHg at 25°C
Melting Point:187 °C
Boiling Point:539.2°Cat760mmHg
PKA:10.98±0.50(Predicted)
Flash Point:279.9°C
PSA：78.60000
Density:1.27g/cm³
LogP:2.96040
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:202.074227566
Heavy Atom Count:15
Complexity:227

Purity/Quality:

97% ^*data from raw suppliers

Methyl4-phenyl-1H-pyrazole-3-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(C=NN1)C2=CC=CC=C2

Technology Process of Methyl 4-phenyl-1H-pyrazole-3-carboxylate

There total 9 articles about Methyl 4-phenyl-1H-pyrazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.2%

: 81190-89-8,1639902-31-0,190263-20-8
methyl 4-bromo-1H-pyrazole-3-carboxylate

: 98-80-6
phenylboronic acid

: 5932-28-5,856061-35-3
4-phenyl-1H-pyrazole-3-carboxylic acid methyl ester

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; In 1,4-dioxane; water; at 150 ℃; for 1h; Microwave irradiation; Inert atmosphere;

Reference yield:

: methyl 4-phenyl-4,5-dihydro-3H-pyrazole-3-carboxylate

: 5932-28-5,856061-35-3
4-phenyl-1H-pyrazole-3-carboxylic acid methyl ester

Guidance literature:: With bromine; In diethyl ether; at 25 ℃; for 0.166667h;
DOI:10.1002/jhet.1654

Reference yield:

: 60676-51-9
methyl (Z)-2-(acetylamino)-3-phenylpropenoate

: 5932-28-5,856061-35-3
4-phenyl-1H-pyrazole-3-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: CHCl₃ / 72 h / Ambient temperature

2: BF₃*Et₂O / 0.25 h / Heating

With boron trifluoride diethyl etherate; In chloroform;