4-Fluoro-4'-methylchalcone

Base Information

Chemical Name:4-Fluoro-4'-methylchalcone
CAS No.:13565-38-3
Molecular Formula:C16H13 F O
Molecular Weight:240.277
Hs Code.:2914700090
European Community (EC) Number:672-673-4
Nikkaji Number:J2.373.804J,J402.929A,J402.943G
Mol file:13565-38-3.mol

Synonyms:4-Fluoro-4'-methylchalcone;13565-38-3;(E)-3-(4-Fluorophenyl)-1-(p-tolyl)prop-2-en-1-one;(E)-3-(4-fluorophenyl)-1-(4-methylphenyl)prop-2-en-1-one;(2E)-3-(4-fluorophenyl)-1-(4-methylphenyl)prop-2-en-1-one;3-(4-fluorophenyl)-1-p-tolylprop-2-en-1-one;(E)-4-Fluoro-4'-methylchalcone;MFCD00017981;STK831844;AKOS003271918;A806965;(E)-3-(4-fluorophenyl)-1-p-tolylprop-2-en-1-one;(2Z)-3-(4-Fluorophenyl)-1-(4-methylphenyl)-2-propen-1-one;(e)-3-(4-fluorophenyl) -1-(4-methylphenyl)prop-2-en-1-one

Suppliers and Price of 4-Fluoro-4'-methylchalcone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2E)-3-(4-Fluorophenyl)-1-(4-methylphenyl)prop-2-en-1-one
500mg
$ 75.00

TCI Chemical
4-Fluoro-4'-methylchalcone
25g
$ 152.00

TCI Chemical
4-Fluoro-4'-methylchalcone
5g
$ 51.00

Crysdot
(E)-3-(4-Fluorophenyl)-1-(p-tolyl)prop-2-en-1-one 95+%
100g
$ 474.00

American Custom Chemicals Corporation
4-FLUORO-4'-METHYLCHALCONE 95.00%
25G
$ 1249.55

Alichem
(E)-3-(4-Fluorophenyl)-1-(p-tolyl)prop-2-en-1-one
100g
$ 507.74

AK Scientific
4-Fluoro-4'-methylchalcone
25g
$ 360.00

AHH
4-Fluoro-4'-methylchalcone 98%
100g
$ 338.00

Total 11 raw suppliers

Chemical Property of 4-Fluoro-4'-methylchalcone

Chemical Property:

Melting Point:119-121 °C
Boiling Point:372.4°Cat760mmHg
Flash Point:173.4°C
PSA：17.07000
Density:1.142g/cm³
LogP:4.03020
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:240.095043196
Heavy Atom Count:18
Complexity:294

Purity/Quality:

97% ^*data from raw suppliers

(2E)-3-(4-Fluorophenyl)-1-(4-methylphenyl)prop-2-en-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 37/39-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(=O)C=CC2=CC=C(C=C2)F
Isomeric SMILES:CC1=CC=C(C=C1)C(=O)/C=C/C2=CC=C(C=C2)F

Technology Process of 4-Fluoro-4'-methylchalcone

There total 11 articles about 4-Fluoro-4'-methylchalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 459-57-4
4-fluorobenzaldehyde

: 122-00-9
para-methylacetophenone

: 13565-38-3,102692-48-8,98991-33-4
3-(4-fluorophenyl)-1-p-tolylprop-2-en-1-one

Guidance literature:: With sodium hydroxide; In ethanol; for 0.0666667h; Microwave irradiation; Green chemistry;

Reference yield: 93.0%

: 706-08-1,5153-69-5
trans-1-(4-fluorophenyl)-2-nitro-ethene

: 104-87-0
4-methyl-benzaldehyde

: 13565-38-3
(E)-3-(4-fluorophenyl)-1-(p-tolyl)prop-2-en-1-one

Guidance literature:: In acetonitrile; at 20 ℃; for 8h; Inert atmosphere; Irradiation; Green chemistry;
DOI:10.1002/adsc.201701559

Reference yield: 88.0%

: 405-99-2
para-fluorostyrene

: 201230-82-2
carbon monoxide

: 624-31-7
4-tolyl iodide

: 13565-38-3
(E)-3-(4-fluorophenyl)-1-(p-tolyl)prop-2-en-1-one

Guidance literature:: With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; 2-((di-adamantan-1-yl)phosphaneyl)-1-(2,6-diisopropylphenyl)-1H-imidazole; triethylamine; In 1,4-dioxane; at 100 ℃; for 20h; under 3750.38 Torr; Autoclave;
DOI:10.1021/ja1059922