N-(4-TERT-BUTYL-PHENYL)-FORMAMIDE

Base Information

• Chemical Name: N-(4-TERT-BUTYL-PHENYL)-FORMAMIDE
• CAS No.: 63429-97-0
• Molecular Formula: C11H15NO
• Molecular Weight: 177.246
• Hs Code.: 2924297099
• Mol file: 63429-97-0.mol

Synonyms:N-Methyl-N-formyl-p-phenylendiamin;3-chloro-2-methylformanilide;6-Chlor-2-formamino-toluol;3'-chloro-o-formotoluidide;4-Formamino-1-tert.-butyl-benzol;

Chemical Property of N-(4-TERT-BUTYL-PHENYL)-FORMAMIDE

Chemical Property:

• Boiling Point: 310.0±21.0 °C(Predicted)
• PKA: 15.00±0.70(Predicted)
• PSA: 32.59000
• Density: 1.025±0.06 g/cm3(Predicted)
• LogP: 3.20190

Purity/Quality:

99% ^*data from raw suppliers

N-(4-tert-Butyl-phenyl)-formamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(4-TERT-BUTYL-PHENYL)-FORMAMIDE

There total 13 articles about N-(4-TERT-BUTYL-PHENYL)-FORMAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

carbon dioxide (124-38-9,18923-20-1) + 4-tert-Butylaniline (769-92-6) → N-(4-(tert-butyl)phenyl)formamide (63429-97-0)

Guidance literature:

With CF₃O₃S^(1-)*C₂₅H₄₂N₆Rh⁽¹⁺⁾; diphenylsilane; In dichloromethane; at 25 ℃; for 24h; under 19001.3 Torr; High pressure; Autoclave;

DOI:10.1002/anie.201504072

Reference yield: 97.0%

→ N-(4-(tert-butyl)phenyl)formamide (63429-97-0)

Guidance literature:

With phenylsilane; sodium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 16h; Inert atmosphere;

Reference yield: 93.0%

4-tert-Butylaniline (769-92-6) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → N-(4-(tert-butyl)phenyl)formamide (63429-97-0)

Guidance literature:

With ammonium iodide; at 125 ℃; for 11h;

DOI:10.1016/j.tetlet.2019.04.040

upstream raw materials:

formic acid

4-tert-Butylaniline

aniline hydrochloride

4-tert-butylnitrobenzene

Downstream raw materials:

4-(1,1-dimethylethyl)-N-methylbenzenamine

4-tert-butyl benzonitrile

isopropyl (4-(tert-butyl)phenyl)carbamate

butyl (4-(tert-butyl)phenyl)carbamate